Cefdinir acid double salt and method for producing the same

++4++42−43−A compound represented by Formula I, wherein M represents Na, K, NH, or Cs; and 1) when Y represents SO: when m=1, then n=1; and when m=0.5, then n=1.5; and 2) when Y represents PO, when m=1, then n=2. The compound has good solubility and high bioavailability and can be formulated into or...

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Main Authors Qi, Youmao, Ye, Fengqi, Jie, Qing, Qi, Yingbei, Zhang, Fengmin, Yu, Baochun, Ye, Tianjian, Yu, Meiping
Format Patent
LanguageEnglish
Published 11.12.2012
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Abstract ++4++42−43−A compound represented by Formula I, wherein M represents Na, K, NH, or Cs; and 1) when Y represents SO: when m=1, then n=1; and when m=0.5, then n=1.5; and 2) when Y represents PO, when m=1, then n=2. The compound has good solubility and high bioavailability and can be formulated into oral pharmaceutical preparations and pharmaceutical preparations for injections.
AbstractList ++4++42−43−A compound represented by Formula I, wherein M represents Na, K, NH, or Cs; and 1) when Y represents SO: when m=1, then n=1; and when m=0.5, then n=1.5; and 2) when Y represents PO, when m=1, then n=2. The compound has good solubility and high bioavailability and can be formulated into oral pharmaceutical preparations and pharmaceutical preparations for injections.
Author Qi, Youmao
Zhang, Fengmin
Yu, Meiping
Ye, Fengqi
Yu, Baochun
Qi, Yingbei
Jie, Qing
Ye, Tianjian
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CorporateAuthor Zhejiang Adamerck Biopharmlabs Inc
Zhejiang Yongning Pharma Co., Ltd
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References (WO 2010075765) 20100700
Kansal et al. (2007/0191602) 20070800
Pozzi et al. (7173126) 20070200
Pozzi et al. (2008/0033169) 20080200
(101481383) 20090700
Pozzi et al. (2009/0036672) 20090200
Lee et al. (6093814) 20000700
Lee et al. (7157576) 20070100
Sturm et al. (6350869) 20020200
Takaya et al. (4559334) 19851200
Pozzi et al. (7405294) 20080700
CN101481383A Translation (Jul. 2009).
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Title Cefdinir acid double salt and method for producing the same
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