Pyrimidinyl pyridone inhibitors of kinases

• Main Authors: Brookfield, Frederick, Eustache, Florence, Dillon, Michael Patrick, Goldstein, David Michael, Gong, Leyi, Han, Xiaochun, Hogg, Joan Heather, Park, Jaehyeon, Reuter, Deborah Carol, Sjogren, Eric Brian
• Format: Patent
• Language: English
• Published: 18.09.2012

123 This application discloses novel pyrimidinyl pyridone derivatives according to formula I, wherein A, R, R, R, and m are defined as described herein, which inhibit JNK. The compounds disclosed herein are useful to modulate the activity of JNK and treat diseases associated with excessive JNK activ...