Cyclic peptide compounds

The present invention relates to a new cyclic peptide compound or a salt thereof, which has anti-hepatitis C virus activities based on inhibitory activity against the RNA replication of hepatitis C virus replicon, to a process for preparation thereof comprising a rearrangement reaction under a mild...

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Main Authors Neya, Masahiro, Yoshimura, Seiji, Kamijyo, Kazunori, Makino, Takuya, Yasuda, Minoru, Yamanaka, Toshio, Tsujii, Eisaku, Yamagishi, Yukiko
Format Patent
LanguageEnglish
Published 28.08.2012
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Abstract The present invention relates to a new cyclic peptide compound or a salt thereof, which has anti-hepatitis C virus activities based on inhibitory activity against the RNA replication of hepatitis C virus replicon, to a process for preparation thereof comprising a rearrangement reaction under a mild acidic condition and the following amino acid changing reactions etc., to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of hepatitis C in a human being or an animal.
AbstractList The present invention relates to a new cyclic peptide compound or a salt thereof, which has anti-hepatitis C virus activities based on inhibitory activity against the RNA replication of hepatitis C virus replicon, to a process for preparation thereof comprising a rearrangement reaction under a mild acidic condition and the following amino acid changing reactions etc., to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of hepatitis C in a human being or an animal.
Author Yamanaka, Toshio
Yoshimura, Seiji
Yasuda, Minoru
Yamagishi, Yukiko
Kamijyo, Kazunori
Makino, Takuya
Tsujii, Eisaku
Neya, Masahiro
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(WO 2006/038088) 20060400
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(WO 2005/032576) 20050400
Office Action dated May 27, 2010, in corresponding Russian Application No. 2008116674.
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