Stable prostaglandin-containing compositions
A pharmaceutical composition containing a prostaglandin and an alkanoic acid ester of a polyethoxylated sorbitol in an amount effective to enhance the chemical stability of the prostaglandin, and the use thereof for treating ophthalmic conditions. Also disclosed are methods for enhancing the chemica...
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Format | Patent |
Language | English |
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27.12.2011
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Abstract | A pharmaceutical composition containing a prostaglandin and an alkanoic acid ester of a polyethoxylated sorbitol in an amount effective to enhance the chemical stability of the prostaglandin, and the use thereof for treating ophthalmic conditions. Also disclosed are methods for enhancing the chemical stability of a prostaglandin-containing composition by using an alkanoic acid ester of a polyethoxylated sorbitol. |
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AbstractList | A pharmaceutical composition containing a prostaglandin and an alkanoic acid ester of a polyethoxylated sorbitol in an amount effective to enhance the chemical stability of the prostaglandin, and the use thereof for treating ophthalmic conditions. Also disclosed are methods for enhancing the chemical stability of a prostaglandin-containing composition by using an alkanoic acid ester of a polyethoxylated sorbitol. |
Author | Heiati, Hashem Visor, Gary C Deaciuc, Victor Hagan, Michael Jette, Karen K Tasko, Peter McAffer, Ian G. C |
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References | Ikegami et al., "9,15-Bis(arylsilyl)prostaglandin F2α derivatives," Chemical Abstracts, 105:650 (1986). (WO-00/40248) 20000700 (704670) 19981000 Kerstetter el al., "Prostaglandin F2 Alpha-1-Isopropylester Lowers Intraocular Pressure Without Decreasing Aqueous Humor Flow", J. Ophthalmol, 105:30-34 (1988). (abstract). Joshi et al. (6319943) 20011100 Woodward et al. (2003/0147823) 20030800 Schneider (5631287) 19970500 Schneider et al. (6011062) 20000100 Weiner et al. (6235781) 20010500 (WO-99/12899) 19990300 Canetta et al. (5670537) 19970900 Ciucanu et al., "Derivatizations of prostaglandins and related compounds to (methoxime) alkyl ester alkyl ether derivatives for gas chromatographic analysis," Chemical Abstracts, 109:664 (1988). Miyazaki et al., "Dimethylisopropylsilyl ether derivatives in gas chromatography mass spectrometry fo prostaglandins and thromboxane B2," Chemical Abstracts, 96:90-91 (1982). (WO-00/20386) 20000400 Lijebris et al., "Ligand-controlled palladium-catalyzed intramolecular reactions of phenyl-substituted prostaglandin F2α analogues," Tetrahedron, 51:9139-9154 (1995). Oda et al., Cell Injury Effect of Isopropyl Unoprostone, an Antiglaucoma Agent, on Cultured Human Conjunctival Cells, J. Ocul Pharmacol Ther., 15:489-496 (1999). (abstract). Ling et al. (2004/0023954) 20040200 (1 321 144) 20030600 Ueno (2004/0076678) 20040400 Castillo et al. (6743439) 20040600 United Kingdom Intellectual Property Office Search Report for corresponding Application No. GB0501192.9, dated Apr. 19, 2005. International Preliminary Report on Patentability for corresponding International Application No. PCT/US2006/001626, dated Jul. 24, 2007. Ruths (1366215) 19210100 Hellberg et al. (2002/0103255) 20020800 Alexander et al., Annals of Pharmacotherpay, 36(3), p. 504-511, 2002. Morozowich et al., "Prostaglandin prodrugs. II: New method for synthesizing prostaglandin C1-aliphatic esters," Chemical Abstracts, 91:603 (1979). Written Opinion of the International Searching Authority for corresponding International Application No. PCT/US2006/001626, dated Jul. 25, 2006. Schneider (5849792) 19981200 Morishima et al. (2004/0097592) 20040500 (WO-2004/022063) 20040300 Klimko et al. (5889052) 19990300 (WO-02/38158) 20020500 Klimko (6417228) 20020700 (WO 98/41208) 19980900 (WO-99/02165) 19990100 Tabassi et al., The Effects of Polysorbate Surfactants on the Structure of Mucus Glycoproteins, http://diglib.tums.ac.ir/U.j/daru/vol9n12/sajjadi.htm, pp:1-10 (2004). Heyl et al. (5165918) 19921100 (WO-95/18102) 19950700 Burk (5972991) 19991000 European Search Report for corresponding Application No. 06178670.0, dated Mar. 18, 2008. (WO-99/02164) 19990100 Ueno (2004/0082660) 20040400 (0603800) 19940600 International Search Report for corresponding International Application No. PCT/US2006/001626, dated Jul. 25, 2006. Waddell et al., "Combined capillary column gas chromatography negative ion chemical ionization mass spectrometry of prostanoids," Chemical Abstracts, 99:87498 (1983). Product page for Sigma T6687 from www.sigmaldrich.com, accessed Dec. 4, 2007. BASF Technical Leaflet, "Cremophor EL", pp:1-7, Jul. 1997. |
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