Protein kinase inhibitors
Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.
Saved in:
Main Authors | , , , , , , , , , , |
---|---|
Format | Patent |
Language | English |
Published |
29.11.2011
|
Online Access | Get full text |
Cover
Loading…
Abstract | Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed. |
---|---|
AbstractList | Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed. |
Author | Fidanze, Steve D Wang, Gary T Wang, Jieyi Erickson, Scott A Mantei, Robert A Sheppard, George S Bell, Randy L Clark, Richard F Hubbard, Robert D Sorensen, Bryan K Ba-Maung, Nwe Y |
Author_xml | – sequence: 1 givenname: Nwe Y surname: Ba-Maung fullname: Ba-Maung, Nwe Y – sequence: 2 givenname: Randy L surname: Bell fullname: Bell, Randy L – sequence: 3 givenname: Richard F surname: Clark fullname: Clark, Richard F – sequence: 4 givenname: Scott A surname: Erickson fullname: Erickson, Scott A – sequence: 5 givenname: Steve D surname: Fidanze fullname: Fidanze, Steve D – sequence: 6 givenname: Robert D surname: Hubbard fullname: Hubbard, Robert D – sequence: 7 givenname: Robert A surname: Mantei fullname: Mantei, Robert A – sequence: 8 givenname: George S surname: Sheppard fullname: Sheppard, George S – sequence: 9 givenname: Bryan K surname: Sorensen fullname: Sorensen, Bryan K – sequence: 10 givenname: Gary T surname: Wang fullname: Wang, Gary T – sequence: 11 givenname: Jieyi surname: Wang fullname: Wang, Jieyi |
BookMark | eNrjYmDJy89L5WSQDCjKL0nNzFPIzsxLLE5VyMzLyEzKLMkvKuZhYE1LzClO5YXS3AwKbq4hzh66pcUFiSWpeSXF8elFiSDKwMLAzNzEwNKYCCUA5qolhw |
ContentType | Patent |
CorporateAuthor | Abbott Laboratories |
CorporateAuthor_xml | – name: Abbott Laboratories |
DBID | EFH |
DatabaseName | USPTO Issued Patents |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EFH name: USPTO Issued Patents url: http://www.uspto.gov/patft/index.html sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
ExternalDocumentID | 08067409 |
GroupedDBID | EFH |
ID | FETCH-uspatents_grants_080674093 |
IEDL.DBID | EFH |
IngestDate | Mon Mar 06 19:17:52 EST 2023 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | English |
LinkModel | DirectLink |
MergedId | FETCHMERGED-uspatents_grants_080674093 |
OpenAccessLink | https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8067409 |
ParticipantIDs | uspatents_grants_08067409 |
PatentNumber | 8067409 |
PublicationCentury | 2000 |
PublicationDate | 20111129 |
PublicationDateYYYYMMDD | 2011-11-29 |
PublicationDate_xml | – month: 11 year: 2011 text: 20111129 day: 29 |
PublicationDecade | 2010 |
PublicationYear | 2011 |
References | Slamon, D., "Use of Chemotherapy plus a Monoclonal Antibody against HER2 for Metastatic Breast Cancer that Overexpresses HER2", New England J. Med. vol. 344(11), pp. 783-792, 2001. Druker, B., "Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia with the Philadelphia Chromosome", New England J of Medicine, vol. 344, p. 1038, 2001. Mathis, G., "HTRF(R) Technology", J. Biomol. Screen, vol. 4(6), pp. 309-314, 1999. (02066481) 20020800 Khandwala, H., "The Effects of Insulin-Like Growth Factors on Tumorigenesis and Neoplastic Growth", Endocrine Reviews, vol. 21, (3), pp. 215-244, 2000. Pure Appl. Chem, "Rules for the Nomenclature of Organic Chemistry, Section E: Stereochemistry", IUPAC Commission on Nomenclature of Organic Chemistry, Pergamon Press,vol. 45, pp. 13-20, 1976. (WO2005068452) 20050700 (03000682) 20030100 (2008029152) 20080300 PCT Search Report for PCT/US2008/084469 mailed on Mar. 18, 2009. (2004110990) 20041200 Rusch, V., "The Epidermal Growth Factor Receptor and Its Ligands as Therapeutic Targets in Human Tumors", Cytokine & Growth Factor Rev. vol. 7, pp. 133-141, 1996. Loewe, et al., "Ein nener Typ der 4-Amino-chinolin-Reihe", Zrzeneim. Forsch, vol. 16,p. 1306-1310, 1966. Davies, D., "Targeting the Epidermal Growth Factor Receptor for Therapy of Carcinomas", Biochem. Pharm. vol. 51 (9), pp. 1101-1110, 1996. Hynes, N., "The biology of erbB-2/neu/HER-2 and its role in cancer", Biochem. Biophys. Acta. vol. 1198, pp. 165-184, 1994. (02066480) 20020800 Catrina S-B et al., "Insulin-like growth factor-I receptor activity is essential for Kaposi's sarcoma growth and survival", Br. J. Cancer, vol. 92, pp. 1467-147, 2005. (2007123892) 20071100 Simone, Oncology: Introduction, Cecil Textbook of Medicine, 20th Edition, vol. 1, pp. 1004-1010, 1996. Lutz, M.P., "Overexpression and Activation of the Tyrosine Kinase Src in Human Pancreatic Carcinoma", Biochemical & Biophysical Research Commun., vol. 243, pp. 503-508, 1998. Talamonti, M., "Increase in Activity and Level of pp60 c-src in Progressive Stages of Human Colorectal Cancer", J. Clin. Invest. vol. 91, pp. 53-60, 1993. (WO2006044869) 20060400 (2006094236) 20060900 (0114375) 20010300 (WO2006068826) 20060600 Hirota, S., "Gain of function Mutations of C-kit in Human Gastrointestinal Stromal Tumors", Science, vol. 279, p. 577-580, 1998. Summy, J., "Src family kinases in tumor progression and metastasis", Cancer & Metastasis Rev. vol. 22, p. 337-358, 2003. |
References_xml | – year: 20080300 ident: 2008029152 – year: 20041200 ident: 2004110990 – year: 20020800 ident: 02066480 – year: 20020800 ident: 02066481 – year: 20010300 ident: 0114375 – year: 20060900 ident: 2006094236 – year: 20030100 ident: 03000682 – year: 20060600 ident: WO2006068826 – year: 20050700 ident: WO2005068452 – year: 20060400 ident: WO2006044869 – year: 20071100 ident: 2007123892 |
Score | 2.8342617 |
Snippet | Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed. |
SourceID | uspatents |
SourceType | Open Access Repository |
Title | Protein kinase inhibitors |
URI | https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8067409 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3PS8MwFH7MMVBPypR1_qAHr9myNm2Ts6wUQelBYbeRpKkGXTbWjv37vnQyvCjklMCXhEfelx_vfQF4mIlE1amoSMy0JMjHNRGZ1ISmkUp5wmqt_Ivu80tavLGnRbLoQXHMhVnhMiIbHEsz2TWbdt0FV6J7PxieHMSfvUag8-oDe_e1llVZ1VOObpf5TL4TTn1o1zwvzuEUIXDL5trmF2nkFzAou9pL6Bk3hKD0kgjWhZ_WIXWE1n1YZf1nN1cQ5vPXx4IccZbvWx-fsqQ__cXX0MdzuhlBSCVjVGdxVknKDOdCRYyrWBidIE3OdADBnzDjf9pu4Ky7yMQSiVvot9uduUMmbNV9N81vbmVoUQ |
link.rule.ids | 230,309,786,808,891,64394 |
linkProvider | USPTO |
linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3JTsMwEB1VBbGcQIAIZcmBq8FNnMQ-Q6OwVTmA1FsUOw5YFLdqUvH7Haeo4gKST7b0bGvkeV5mngGuhyKSdSwqEjJVEuTjmoikVITGgYx5xGol3YvuyzjO3tjjJJr0INvkwnzhMiJzHEtzs2zm7awLrkT3vjY8WYs_O41A69QHvu10VlZ5Vd9ydLvMZfJtOY51KvqjNNuHXQTBTZttm1-0kR7Adt7VHkJP2yPwcieKYKz_aSySh2_sh5HGfXdzDH46er3LyAaneF-4CJWC_vQYnkAfT-r6FHxaMkZVEiZVSZnmXMiAcRkKrSIkyqHywPsT5uyftivYye_T4vlh_DSAve5WE0sgzqHfLpb6AmmxlZfdjFe7jWtL |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=Protein+kinase+inhibitors&rft.inventor=Ba-Maung%2C+Nwe+Y&rft.inventor=Bell%2C+Randy+L&rft.inventor=Clark%2C+Richard+F&rft.inventor=Erickson%2C+Scott+A&rft.inventor=Fidanze%2C+Steve+D&rft.inventor=Hubbard%2C+Robert+D&rft.inventor=Mantei%2C+Robert+A&rft.inventor=Sheppard%2C+George+S&rft.inventor=Sorensen%2C+Bryan+K&rft.inventor=Wang%2C+Gary+T&rft.inventor=Wang%2C+Jieyi&rft.number=8067409&rft.date=2011-11-29&rft.externalDBID=n%2Fa&rft.externalDocID=08067409 |