Ribonucleotide reductase inhibitors and methods of use

Provided herein are novel compounds that inhibit ribonucleotide reductase (RR) by binding to RRM2 and interfering with the activity of the RRM1/RRM2 holoenzyme. These inhibitors may be used to inhibit RR activity and to treat various conditions associated with RRM2 expression, such as for example ce...

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Bibliographic Details
Main Authors Yen, Yun, Horne, David, Yuan, Yate-Ching, Zhou, Bing-Sen, Perkins Harki, Angela L, Su, Leila
Format Patent
LanguageEnglish
Published 07.06.2011
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