Methods of analyzing samples using broadband laser light
Broadband light, for example, from a Fabry-Perot quantum cascade laser, is shone onto a sample, and spectral data concerning the broadband light reflected from the sample is collected. The spectral data is analyzed to determine information about one or more substances in the sample. For example, if...
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Format | Patent |
Language | English |
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22.02.2011
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Abstract | Broadband light, for example, from a Fabry-Perot quantum cascade laser, is shone onto a sample, and spectral data concerning the broadband light reflected from the sample is collected. The spectral data is analyzed to determine information about one or more substances in the sample. For example, if the sample contains micro-organisms, such as bacteria or fungus, the biological classification(s) (e.g., species) of the micro-organisms can be determined from the spectral data. As another example, if the sample contains virus, the biological classification(s) (e.g., species) of the virus(es) can be determined from the spectral data. As yet another example, if the sample contains particles, size, location and velocity can be determined from the spectral data. |
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AbstractList | Broadband light, for example, from a Fabry-Perot quantum cascade laser, is shone onto a sample, and spectral data concerning the broadband light reflected from the sample is collected. The spectral data is analyzed to determine information about one or more substances in the sample. For example, if the sample contains micro-organisms, such as bacteria or fungus, the biological classification(s) (e.g., species) of the micro-organisms can be determined from the spectral data. As another example, if the sample contains virus, the biological classification(s) (e.g., species) of the virus(es) can be determined from the spectral data. As yet another example, if the sample contains particles, size, location and velocity can be determined from the spectral data. |
Author | Puzey, Kenneth A |
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References | Velsko et al. (6421166) 20020700 Hill et al. (2003/0223063) 20031200 Clair Gmachl et al., "Minimal Group Refractive Index Dispersion and Gain Evolution in Ultra-Broadband Quantum Cascade Laser" Dec. 2002, IEEE Photonics Technology letters, vol. 14. Chew, III (4149805) 19790400 Second Office Action after RCE dated Oct. 14, 2008, with regard to related U.S. Appl. No. 11/087,939, filed Mar. 22, 2005, Puzey. Quantitative Gas Sensing by Backscatter-Absorption Measurements of a Pseudo-Random Code Modulated λ ˜ 8 μm Quantum Cascade Laser; C.M. Gittins, E.T. Wetjen, C. Gmachl, F. Capasso, A.L. Hutchinson, D.L. Sivco, J.N. Baillargeon, A.Y. Cho; Optics Letters 25(16), 1162-1164 (Aug. 15, 2000) Optical Society of America. Preliminary Amendment accompanying first RCE dated Dec. 3, 2007, with regard to related U.S. Appl. No. 11/087,939, filed Mar. 22, 2005, Puzey. Gunning et al. (4508964) 19850400 Ray et al. (6608677) 20030800 Ankerhold (2001/0025927) 20011000 Measurement of nitric oxide with an antimonide diode laser; Daniel B. Oh and Alan C. Stanton; Applied Optics, vol. 36, No. 15, pp. 3294-3297, May 2, 1997. Lee et al. (6593582) 20030700 Slater (2004/0252300) 20041200 Owen (4054389) 19771000 Supplemental Preliminary Amendment dated Dec. 6, 2007, with regard to related U.S. Appl. No. 11/087,939, filed Mar. 22, 2005, Puzey. First Office Action after RCE dated Dec. 26, 2007, with regard to related U.S. Appl. No. 11/087,939, filed Mar. 22, 2005, Puzey. Sub-part-per-billion detection of nitric oxide in air using a thermoelectrically cooled mid-infrared quantum cascade laser spectrometer; D.D. Nelson, J.H. Shorter, J.B. McManus, M.S. Zahniser; Applied Physics B-Lasers and Optics 75, 343-350 (2002. Buchsbaum et al. (6700690) 20040300 Lendl (2004/0211906) 20041000 Blaser et al., "High power and single frequency quantum cascade lasers for gas sensing" Jan. 2004, Proceedings of SPIE vol. 5240, pp. 137-141. Lepper et al. (6278522) 20010800 Capasso et al. (7010010) 20060300 Geiger (5250810) 19931000 Response to First Office Action after RCE dated Jun. 26, 2008, with regard to related U.S. Appl. No. 11/087,939, filed Mar. 22, 2005, Puzey. Yguerabide et al. (6586193) 20030700 Kosterev, Anatoliy A. et al., "Chemical Sensors Based on Quantum Cascade Lasers" IEEE Journal of Quantum Electronics, vol. 38, No. 6, Jun. 2002, pp. 528-591. Amendment and Response to First Office Action dated Mar. 19, 2007, with regard to related U.S. Appl. No. 11/087,939, filed Mar. 22, 2005, Puzey. Friberg et al. (2003/0218750) 20031100 First Office Action dated Nov. 17, 2006, with regard to related U.S. Appl. No. 11/087,939, filed Mar. 22, 2005, Puzey. Taylor (5373160) 19941200 Webber et al. (2002/0158202) 20021000 Notice of Allowance dated Jul. 29, 2009, with regard to related U.S. Appl. No. 11/087,939, filed Mar. 22, 2005, Puzey. Yeh et al. (4269481) 19810500 Final Office Action dated Jun. 5, 2007, with regard to related U.S. Appl. No. 11/087,939, filed Mar. 22, 2005, Puzey. Alexander Soibel et al., "Active Mode Locking of Broadband Quantum Cascade Lasers" Jul. 2004, IEEE Journal of Quantum Electronics, vol. 40. Response to Second Office Action after RCE dated Apr. 14, 2009, with regard to related U.S. Appl. No. 11/087,939, filed Mar. 22, 2005, Puzey. Thermoelectrically cooled quantum cascade laser based sensor for continuous monitoring of ambient atmospheric CO; A.A. Kosterev, F.K. Tittel, R. Kohler, C. Gmachl, F. Capasso, D.L. Sivco, A.Y.Cho, S. Wehe and M. Allen; Optical Society of America ; Applied Optics, vol. 41, No. 6, 2002. Wilkes et al. (2002/0138210) 20020900 Levenson et al. (2003/0030801) 20030200 Bove et al. (2004/0024540) 20040200 |
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