Process for renaturation of recombinant, disulfide containing proteins at high protein concentrations in the presence of amines

A method for renaturation of proteins comprising adding to a solution of denatured, chemically modified or reduced proteins a refolding buffer containing a primary, secondary or tertiary amine. Said method has been applied, for example, to interleukin-4 and bovine pancreatic trypsin inhibitor (BPTI)...

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Bibliographic Details
Main Authors Peters, Jörg, Minuth, Torsten
Format Patent
LanguageEnglish
Published 22.02.2011
Online AccessGet full text

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