Nucleic acid and corresponding protein entitled STEAP-1 useful in treatment and detection of cancer

• Main Authors: Faris, Mary, Ge, Wangmao, Raitano, Arthur B, Challita-Eid, Pia M, Jakobovits, Aya
• Format: Patent
• Language: English
• Published: 08.02.2011

A novel gene 08P1D4 (also designated STEAP-1) and its encoded protein, and variants thereof, are described wherein STEAP-1 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, STEAP-1 provides a diagnostic, prognostic...