Plasmonic laser nanoablation methods

A novel femtosecond laser nano-ablation technique called Plasmonic Laser Nano-Ablation (PLN). The technique takes advantage of surface-enhanced plasmonic scattering of ultrashort laser pulses by nanoparticles to vaporize sub-cellular structures in attoliter volumes. The use of nanoparticles may over...

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Main Authors Ben-Yakar, Adela, Eversole, Daniel, Guo, Xun
Format Patent
LanguageEnglish
Published 16.11.2010
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Abstract A novel femtosecond laser nano-ablation technique called Plasmonic Laser Nano-Ablation (PLN). The technique takes advantage of surface-enhanced plasmonic scattering of ultrashort laser pulses by nanoparticles to vaporize sub-cellular structures in attoliter volumes. The use of nanoparticles may overcome problems associated with current FLMS techniques and does not rely on heating for nanodisruption. In PLN, the particle acts as a "nano-lens," restricting laser light to the near-field of the particle, and only photodisrupting structures that are nanometers away. This eliminates the need for a tightly focused beam, while still achieving nanoscale ablation resolution. Moreover, the enhanced scattering around the particles reduces the amount of required laser fluence. A method is provided comprising positioning a nanoparticle in proximity to a surface of a material; irradiating the nanoparticle with a laser tuned close to the nanoparticle's plasmonic frequency; and allowing a near-field effect from the irradiated nanoparticle to photodamage the material.
AbstractList A novel femtosecond laser nano-ablation technique called Plasmonic Laser Nano-Ablation (PLN). The technique takes advantage of surface-enhanced plasmonic scattering of ultrashort laser pulses by nanoparticles to vaporize sub-cellular structures in attoliter volumes. The use of nanoparticles may overcome problems associated with current FLMS techniques and does not rely on heating for nanodisruption. In PLN, the particle acts as a "nano-lens," restricting laser light to the near-field of the particle, and only photodisrupting structures that are nanometers away. This eliminates the need for a tightly focused beam, while still achieving nanoscale ablation resolution. Moreover, the enhanced scattering around the particles reduces the amount of required laser fluence. A method is provided comprising positioning a nanoparticle in proximity to a surface of a material; irradiating the nanoparticle with a laser tuned close to the nanoparticle's plasmonic frequency; and allowing a near-field effect from the irradiated nanoparticle to photodamage the material.
Author Ben-Yakar, Adela
Eversole, Daniel
Guo, Xun
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References Liu et al., "Measuring plasmon-resonance enhanced third harmonic (3) of Ag nanoparticles", Appl. Phys. Lett. 89, 041322, 2006.
M. Quinten, "Local Fields close to the surface of nanoparticles and aggregrates of particles." Appl. Phys. B 73, 2001, pp. 245-255.
Yanik, et al., "Functional regeneration after laser axotomy." Nature 432, 2004, p. 882.
Huttmann, et al., "High precision cell surgery with nanoparticles?" Med. Laser Appl. 17, 2002, pp. 9-14.
Messinger, et al., "Local fields at the surface of noble-metals microspheres." Phys Rev B 24(2), 1981, pp. 649-657.
Plech,et al., "Femtosecond laser near-field ablation from gold particles." Nature Physics 2, 2006, pp. 44-47.
West et al. (6530944) 20030300
Huang et al., "Determination of the Minimum Temperature Required for Selective Photothermal Destruction of Cancer Cells with the Use of Immunotargeted Gold Nanoparticles", Photochemistry and Photobiology 2006 (82) 412-417.
Pitsillides, et al., "Selective cell targeting with light-absorbing microparticles and nanoparticles." Biophys. J. 84, 2003, pp. 4023-4032.
Kelly, et al., "The optical properties of metal nanoparticles: the influence of size, shape, and dielectric environment." J. Phys. Chem. B 107, 2003, pp. 668-677.
Lee et al. (2008/0241262) 20081000
Oldenburg et al. (6344272) 20020200
Huttmann, et al., "Model system for investigating laser-induced subcellular microeffects." Proc. SPIE, 2001, vol. 4257, pp. 398-409.
Adela Ben-Yakar, "NER: Nanoparricle-Assisted Plasmonic Laser Surgery", NSF Award # 0508266, Jun. 3, 2005.
O'Neal, et al., "Photo-thermal tumor ablation in mice using near infrared-absorbing nanoparticles." Cancer Lett., 2004.
Farahi et al. (2003/0193982) 20031000
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