Sulfoximine-substituted pyrimidines, processes for production thereof and use thereof as drugs

The invention relates to sulfoximine-substituted pyrimidines of the general formula I processes for the preparation thereof and their use as drugs.

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Main Authors Lücking, Ulrich, Nguyen, Duy, Von Bonin, Arne, Von Ahsen, Oliver, Krüger, Martin, Briem, Hans, Kettschau, Georg, Prien, Olaf, Mengel, Anne, Konrad, Krolikiewicz, Boemer, Ulf, Bothe, Ulrich, Hartung, Ingo
Format Patent
LanguageEnglish
Published 02.11.2010
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Abstract The invention relates to sulfoximine-substituted pyrimidines of the general formula I processes for the preparation thereof and their use as drugs.
AbstractList The invention relates to sulfoximine-substituted pyrimidines of the general formula I processes for the preparation thereof and their use as drugs.
Author Von Bonin, Arne
Lücking, Ulrich
Briem, Hans
Konrad, Krolikiewicz
Nguyen, Duy
Bothe, Ulrich
Prien, Olaf
Hartung, Ingo
Krüger, Martin
Kettschau, Georg
Von Ahsen, Oliver
Boemer, Ulf
Mengel, Anne
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References Fabbro et al. Pharmacology & therapeutics 93, 7.
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Mass, R. D., Int. J. Radiation Oncology Bio. Phys. vol. 58(3): 932-940, 2004.
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Powell et al., British Journal of Dermatology, 141: 802-810, 1999.
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Cecil Textbook of Medicine, edited by Bennet, J.C., and Plum F., 20th edition,vol. 1, 1004-1010, 1996.
Cohen et al., Current Opinion in Chemical Biology, 3,459-465, 1999.
Dermer et al., Bio/Technology, 1994, 12:320.
Freshney et al.,Culture of Animal Cells, A Manual of Basic Technique, Alan R. Liss, Inc., 1983, New York, p. 4.
Luecking et al. (2004/0063737) 20040400
Luecking et al. (2005/0176743) 20050800
Golub et al., Science, 286, 531-537, 1999.
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