Antigens and vaccines against
Piscirickettsia salmonisPiscirickettsia salmonisThe present invention discloses novel proteins, e.g., antigens, from . The present invention further discloses nucleic acids that encode these proteins. The present invention also discloses the use of the proteins, e.g., antigens, and nucleic acids to...
Saved in:
Main Authors | , |
---|---|
Format | Patent |
Language | English |
Published |
12.10.2010
|
Online Access | Get full text |
Cover
Loading…
Abstract | Piscirickettsia salmonisPiscirickettsia salmonisThe present invention discloses novel proteins, e.g., antigens, from . The present invention further discloses nucleic acids that encode these proteins. The present invention also discloses the use of the proteins, e.g., antigens, and nucleic acids to prepare vaccines against salmonid rickettsial septicemia (SRS). The present invention also discloses vaccines that can be used to protect fish from , as well as other pathogens. In addition, the present invention discloses methods of using the vaccines of the present invention to protect fish from SRS as well as from other pathogenic diseases. |
---|---|
AbstractList | Piscirickettsia salmonisPiscirickettsia salmonisThe present invention discloses novel proteins, e.g., antigens, from . The present invention further discloses nucleic acids that encode these proteins. The present invention also discloses the use of the proteins, e.g., antigens, and nucleic acids to prepare vaccines against salmonid rickettsial septicemia (SRS). The present invention also discloses vaccines that can be used to protect fish from , as well as other pathogens. In addition, the present invention discloses methods of using the vaccines of the present invention to protect fish from SRS as well as from other pathogenic diseases. |
Author | Francis, Michael James Kirke, David Francis |
Author_xml | – sequence: 1 givenname: David Francis surname: Kirke fullname: Kirke, David Francis – sequence: 2 givenname: Michael James surname: Francis fullname: Francis, Michael James |
BookMark | eNrjYmDJy89L5WSQdcwryUxPzStWSMxLUShLTE7OzEsFctITM_OKS3gYWNMSc4pTeaE0N4OCm2uIs4duaXFBYklqXklxfHpRIogyMLcwNDS1MDYmQgkAeEUmsQ |
ContentType | Patent |
CorporateAuthor | Intervet International B.V |
CorporateAuthor_xml | – name: Intervet International B.V |
DBID | EFH |
DatabaseName | USPTO Issued Patents |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EFH name: USPTO Issued Patents url: http://www.uspto.gov/patft/index.html sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
ExternalDocumentID | 07811583 |
GroupedDBID | EFH |
ID | FETCH-uspatents_grants_078115833 |
IEDL.DBID | EFH |
IngestDate | Sun Mar 05 22:45:03 EST 2023 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | English |
LinkModel | DirectLink |
MergedId | FETCHMERGED-uspatents_grants_078115833 |
OpenAccessLink | https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7811583 |
ParticipantIDs | uspatents_grants_07811583 |
PatentNumber | 7811583 |
PublicationCentury | 2000 |
PublicationDate | 20101012 |
PublicationDateYYYYMMDD | 2010-10-12 |
PublicationDate_xml | – month: 10 year: 2010 text: 20101012 day: 12 |
PublicationDecade | 2010 |
PublicationYear | 2010 |
References | Greenspan et al (Nature Biotechnology 7: 936-937, 1999). Greenspan, N.S., et al., "Defining epitopes: It's not as easy as it seems", Nature Biotechnology, vol. 17 pp. 936-937 (1999). Rollenhagen, C., et al., "Antigen selection based on expression levels during infection facilitates vaccine development for an intracellular pathogen", PNAS, vol. 101, No. 23, pp. 8739-8744 (2004). Vakharia (6936256) 20050800 Barnes, M.N., et al., "Purification of Piscirickettsia salmonis and partial characteriation of antigens", Diseases of Aquatic Organisms, vol. 33, pp. 33-41 (1998). Smith, P.A., et al., "Routes of entry of Piscirickettsia salmonis in rainbow trout Oncorhynchus mykiss", Diseases of Aquatic Organisms, vol. 37, pp. 165-172 (1999). Jorgensen, J.B., et al., "CpG oligodeoxynucleotides and plasmid DNA stimulate Atlantic salmon (Salmo salar L.) leucocytes to produce supernatants with antiviral activity", Development & Comparative Immunology, vol. 25, pp. 313-321 (2001). Chothia et al (The EMBO Journal, 1986, 5/4:823-26). Challita-Eid et al. (2003/0166526) 20030900 Hyung, J., et al., "A gene cluster encoding malonyl-CoA decarboxylase (MatA), malonyl-CoA synthetase (MatB) and a putative dicarboxylate carrier protein (MatC) in Rhizobium trifolii", Eur. J. Biochem., vol. 257, pp. 395-402 (1998). Mikayama et al. (Nov. 1993. Proc.Natl.Acad.Sci. USA, vol. 90 : 10056-10060). Valenzuela, P., et al., "Sequence and Applications of the Piscirickttsia salmonis Genome", Biological Research, vol. 34, No. 3-4 (2001). Thacker, E.L., "Detection of intracellular porcine reproductive and respiratory syndrome virus nucleocapsid protein in porcine macrophages by flow cytometry", J. Vet. Diagn. Invest., vol. 10, pp. 308-311 (1998). (3113-2001) 20011200 Houghten, R.A., et al., "New Approaches to Immunization Developing Vaccines Against Parasitic, Bacterial, and Viral Diseases", Vaccines86, Cold Spring Harbor Laboratory, pp. 21-25 (1986). Kuzyk, M.A., et al., "Antigenic Characterization of the Salmonid Pathogen Piscirickettsia salmonis", Infection and Immunity, vol. 64, No. 12, pp. 5205-5210 (1996). Jones, S., et al., "Virulence and antigenic characteristics of a cultured Rickettsiales-like organisum isolated from farmed Atlantic salmon Salmo salar in eastern Canada", Diseases of Aquatic Organisms, vol. 33, pp. 25-31 (1998). Tighe, H., et al., "Gene vaccination: plasmid DNA is more than just a blueprint", Immunology Today, vol. 19, No. 2 pp. 89-97 (1998). Leong (5165925) 19921100 Henriquez, V., et al., "An Alternative Efficient Procedure for Purification of the Obligate Intracellular Fish Bacterial Pathogen Piscirickettsia salmonis", Applied and Environmental Microbiology, vol. 69, No. 10, pp. 6268-6271 (2003). (WO 2005/035558) 20050400 Cross, M.L., et al., "Intracellular survival of virulent Mycobacterium bovis and M. bovis BCG in ferret Macrophages", Veterinary Microbiology, vol. 66, pp. 235-243 (1999). Morzunov, S., et al., "The complete genome structure and phylogenetic relationship of infectious hematopoietic necrosis virus", Virus Research, vol. 38, pp. 175-192 (1995). Gudding, R., et al., "Recent developments in fish vaccinology", Veterinary Immunology and Immunopathology, vol. 72, pp. 203-212 (1999). (WO 02/38770) 20020500 (1049-2003) 20030500 New England Biolabs Catalog, p. 111 (1996/1997). Harlow, E., et al., "Antibodies A Laboratory Manual", Cold Spring Harbor Laboratory Press Inc., pp. 23-27, 25-33 and 72-74 (1988). Mauel, M., et al., "Piscirickettsiosis and piscirickettsiosis-like infections in fish: a review", Veterinary Microbiology, vol. 87, pp. 279-289 (2002). Thiry et al. (2007/0207165) 20070900 Wilhelm, V., "The complete sequence of the mitochondrial genome of the Chinook salmon, Oncorhynchus tshawytsche", Biol. Res., vol. 36, pp. 223-231 (2003). Molling, K., et al., "Naked DNA for vaccines or therapy", J. Mol. Med., vol. 75, pp. 242-246 (1997). Simard et al. (6887989) 20050500 Wilhelm, V., "Cloning and expression of the coding regions of the heat shock proteins HSP10 and HSP16 from Piscirickettsia salmonis", Biol. Res. vol. 36, pp. 421-428 (2003). Wells, T., et al., "The chemokine information source: identification and characterization of novel chomokines using the WorldWideWeb and Expressed Sequence Tag Databases", vol. 61, pp. 545-550 (1997). PCT International Search Report dated Sep. 23, 2005 for corresponding PCT Application No. PCT/IB2004/003339. Gerhold, D., et al., "It's the genes! EST access to human genome content", BioEssays, vol. 18, No. 12, pp. 973-981 (1996). (3112-2001) 20011200 Schade, B., et al., "Toxoplasma gondii induction of interleukin-12 is associated with acute virulence in mice and depends on the host genotype", Veterinary Parasitology, vol. 100, pp. 63-74 (2001). Kuzyk et al. (2005/0002946) 20050100 Havarstein, L.S., et al., "Sequence of the large double-stranded RNA segment of the N1 strain of infectious pancreatic necrosis virus: a comparison with other Birnaviridae", Journal of General Virology, vol. 71, pp. 299-308 (1990). Stowers, et al., "Vaccination of Monkeys with Recombinant Plasmodium falciparum Apical Membrane Antigen 1 Confers Protection against Blood-Stage Malaria", Infection and Immunity, vol. 70, No. 12, pp. 6961-6967 (2002). Didier, E.S., et al., "Epidemiology of microsporidiosis: sources and modes of transmission", Veterinary Parasitology, vol. 126, pp. 145-166 (2004). Salonius et al. (7302913) 20071200 (WO 01/68865) 20010900 (WO 01/49712) 20010700 Henriquez, V.B., et al., "Improved Purification of The Obligate Intracelluar", 102nd General Meeting of the American Society for Microbiology, (Abstract). Bravo, S., et al., "Coho Salmon Syndrome in Chile," FHS/AFS Newsletter, vol. 17, No. 2, p. 3 (1989). Herbert, W.J., et al., Definition of Vaccine: The Dictionary of Immunology, Academic Press (1995). Rudinger et al. (Jun. 1976. Peptide Hormones. Biol.Council. pp. 5-7). Leong, J.C., et. al., "Fish Vaccine Antigens Produced or Delivered by Recombinant DNA Technologies", Dev. Biol. Stand. Basel, Karger, vol. 90 pp. 267-277 (1997). Argenton, F., et al., "Use of random DNA amplification to generate specific molecular probes for hybridization tests and PCR-based diagnosis of Yersinia ruckeri", Diseases of Aquatic Organisms, vol. 24, pp. 121-127 (1996). Ellis, R.W., "New Technologies for Making Vaccines", Vaccines, Chapter 29, pp. 568-575 (1988). (WO 2006/037383) 20060400 Miquel, A., et al., "Immunoresponse of Coho salmon immunized with a gene expression library from Piscirickettsia salmonis", Biol. Res., vol. 36, pp. 313-323 (2003). (1048-2003) 20030500 Pryde, W.T., "Nucleotide sequence analysis of the serotype-specific epitope of infectious pancreatic necrosis virus", Arch Virol, vol. 129, pp. 287-293 (1993). (0712926) 19960500 (3110-2001) 20011200 Lederer, J., et al., "Haemophilus somnus," a Facultative Intracellular Pathogen of Bovine Mononuclear Phagocytes, Infection and Immunity, vol. 55, No. 2, pp. 381-387 (1987). Bork, P., "Powers and Pitfalls in Sequence Analysis: The 70% Hurdle", Genome Research, vol. 10, pp. 398-400 (2000). (2086-2001) 20010800 Kuzyk et al. (2004/0086524) 20040500 (1047-2003) 20030500 Russmann, H., et al., "Attenuated Yersinia pseudotuberculosis Carrier Vaccine for Simultaneous Antigen-Specific CD4 and CD8 T-Cell Induction", Infection and Immunity, vol. 71, No. 6, pp. 3463-3472 (2003). Gonzalez (2003/0147909) 20030800 Dittmer, U., et al., "Treatment of infectious diseases with immunostimulatory oligodeoxynucleotides containing CpG motifs", Current Opinion in Microbiology, vol. 6, pp. 472-477 (2003). (3111-2001) 20011200 Colman, P.M., "Effects of amino acid sequence changes on antibody-antigen interactions", Research in Immunology, vol. 145, pp. 33-36 (1994). Blastp Serach Results (May 26, 2009). (2 356 632) 20010500 NCBI Blast Search-Acholeplasma Laidlawii PG-8A. |
References_xml | – year: 20030500 ident: 1048-2003 – year: 20011200 ident: 3112-2001 – year: 20071200 ident: 7302913 contributor: fullname: Salonius et al. – year: 20040500 ident: 2004/0086524 contributor: fullname: Kuzyk et al. – year: 19960500 ident: 0712926 – year: 20010500 ident: 2 356 632 – year: 20010700 ident: WO 01/49712 – year: 20010900 ident: WO 01/68865 – year: 20030900 ident: 2003/0166526 contributor: fullname: Challita-Eid et al. – year: 19921100 ident: 5165925 contributor: fullname: Leong – year: 20050800 ident: 6936256 contributor: fullname: Vakharia – year: 20050100 ident: 2005/0002946 contributor: fullname: Kuzyk et al. – year: 20050400 ident: WO 2005/035558 – year: 20010800 ident: 2086-2001 – year: 20030500 ident: 1047-2003 – year: 20030800 ident: 2003/0147909 contributor: fullname: Gonzalez – year: 20011200 ident: 3111-2001 – year: 20060400 ident: WO 2006/037383 – year: 20011200 ident: 3110-2001 – year: 20050500 ident: 6887989 contributor: fullname: Simard et al. – year: 20070900 ident: 2007/0207165 contributor: fullname: Thiry et al. – year: 20030500 ident: 1049-2003 – year: 20011200 ident: 3113-2001 – year: 20020500 ident: WO 02/38770 |
Score | 2.7792702 |
Snippet | Piscirickettsia salmonisPiscirickettsia salmonisThe present invention discloses novel proteins, e.g., antigens, from . The present invention further discloses... |
SourceID | uspatents |
SourceType | Open Access Repository |
Title | Antigens and vaccines against |
URI | https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7811583 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfVxNawIxEB1UCtWTosWPKnvwmrqsG80eRVwWD8WDgjfZxKyXNoqJ9u87E4v0Yo9JYJIQJi-TefMAhhHCmhITzWKpFAYoIWf4SkiYoJRSIZKpzr3a5-ck28TLLd-WIHvUwnyjG7ETrsV-XOzJHT25Eq_3-8Gzu_gzaQQaUh_4MV_HfL_aFyOqmORiXIayCInatUizGryiCXyyGWf_gEZah5eV721ASZsm9GfGkfSlDTB4D665opQ2Ng4Ym1vXgiBdrOcZe9jaHc7EUdmFv3OO36CCsbpuE1FIcR4VUiqEPZ1PZYwepaWi35BIhqIDnadmuv-M9aDq09aeSvEOFXe-6D6ioZMDv9UbQtRpCQ |
link.rule.ids | 230,309,786,808,891,64396 |
linkProvider | USPTO |
linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQMQJWa8kWZqm6JknJycAOioGpLrCVYKlrAZpSSrOwNE9NBJ_26WfmEWriFWEawcTgAd8LkwvMRroFQLcU65UWF5TkgxdXAot3SMTrQg5_Bp0RmAc6faA8Lyc_MSUgJU0ftGPS1MKYmYEVVMeC0rqrmwc3AyfQEGCjLa-kGKnacBNkYAsAiwoxMKXmiTDIOuaVgA6_LFYAdt8VyhKTQZPaQE46sHdeXCLKoODmGuLsoQs3Kz69CLRKJd4AaquxGAMLsLeeKgFaKpRsamqUlpSUDKz4UhPNk0yAeSo1KRk0HmKUZGAhySCJ0xgpPHLyDBwBLm7xPp5-3tIMXOA5bPC6ChkGlpKi0lRZYNVYkiQH9jUAmpRsBQ |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=Antigens+and+vaccines+against&rft.inventor=Kirke%2C+David+Francis&rft.inventor=Francis%2C+Michael+James&rft.number=7811583&rft.date=2010-10-12&rft.externalDBID=n%2Fa&rft.externalDocID=07811583 |