4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine derivative or salt thereof
A novel 4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine derivative or a pharmaceutically acceptable salt thereof, which is useful as an agent for treating or preventing nocturia and/or diabetes insipidus, is provided.
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Format | Patent |
Language | English |
Published |
05.10.2010
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Abstract | A novel 4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine derivative or a pharmaceutically acceptable salt thereof, which is useful as an agent for treating or preventing nocturia and/or diabetes insipidus, is provided. |
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AbstractList | A novel 4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine derivative or a pharmaceutically acceptable salt thereof, which is useful as an agent for treating or preventing nocturia and/or diabetes insipidus, is provided. |
Author | Tsukamoto, Issei Koshio, Hiroyuki Saitoh, Chikashi Akamatsu, Seijiro Kakefuda, Akio |
Author_xml | – sequence: 1 givenname: Hiroyuki surname: Koshio fullname: Koshio, Hiroyuki – sequence: 2 givenname: Issei surname: Tsukamoto fullname: Tsukamoto, Issei – sequence: 3 givenname: Akio surname: Kakefuda fullname: Kakefuda, Akio – sequence: 4 givenname: Seijiro surname: Akamatsu fullname: Akamatsu, Seijiro – sequence: 5 givenname: Chikashi surname: Saitoh fullname: Saitoh, Chikashi |
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References | Canadian Office Action (2 pages) mailed Nov. 2, 2009, in corresponding application No. 2,521,492. (WO 95/34540) 19951200 European Office Action (5 pages) mailed Feb. 23, 2010, in corresponding application No. 04 729 502.7. (WO-95/06035) 19950300 Matsuhisa et al. (6340678) 20020100 (1445253) 20040800 Ogawa et al. (6335327) 20020100 Office Action received Aug. 31, 2007, in related application 2005136863. Koshio et al. (7183271) 20070200 (WO 03/042181) 20030500 (9-221475) 19970800 (2 137 760) 19990900 Ogawa et al. (6642223) 20031100 (WO-97/22591) 19970600 Neal et al. (6547395) 20030400 (WO-99/06409) 19990200 Del Tredici et al., Identification of Novel Selective V.sub.2 Receptor Non-Peptide Agonists, Biochemical Pharmacology, vol. 76, pp. 1134-1141, 2008. Ogawa et al. (6096735) 20000800 (WO-00/46224) 20000800 Israeli Office Action (1 page) mailed Aug. 17, 2009, in corresponding application No. 171332. Taniguchi et al. (5710150) 19980100 (3215910) 20010800 Kondo et al., "Novel Design of Nonpeptide AVP V2 Receptor Agonists: Structural Requirements for and Agonist Having 1-(4-AminobenzoyI)-2,3,4,5-tetrahydro-1H-1-benzazepine as a Template," J. med. Chem. (Nov. 2000) vol. 43, No. 23, pp. 4388-4397. (2000-351768) 20001200 European Search Report received Jun. 25, 2008, in corresponding application EP 04 72 9502. (8-301848) 19961100 (11-349570) 19991200 Ogawa et al. (6096736) 20000800 (9-221476) 19970800 Ogawa et al.; "Pharmaceutical Composition"; Patent Abstracts of Japan of JP 11-060488, Mar. 2, 1999. Ogawa et al. (2002/0049194) 20020400 (WO-01/49682) 20010700 (WO-98/39325) 19980900 Ashworth et al. (2003/0087892) 20030500 (0716083) 19960600 (0987264) 20000300 (WO-99/06403) 19990200 (2926335) 19990500 |
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