4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine derivative or salt thereof

A novel 4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine derivative or a pharmaceutically acceptable salt thereof, which is useful as an agent for treating or preventing nocturia and/or diabetes insipidus, is provided.

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Main Authors Koshio, Hiroyuki, Tsukamoto, Issei, Kakefuda, Akio, Akamatsu, Seijiro, Saitoh, Chikashi
Format Patent
LanguageEnglish
Published 05.10.2010
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Abstract A novel 4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine derivative or a pharmaceutically acceptable salt thereof, which is useful as an agent for treating or preventing nocturia and/or diabetes insipidus, is provided.
AbstractList A novel 4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine derivative or a pharmaceutically acceptable salt thereof, which is useful as an agent for treating or preventing nocturia and/or diabetes insipidus, is provided.
Author Tsukamoto, Issei
Koshio, Hiroyuki
Saitoh, Chikashi
Akamatsu, Seijiro
Kakefuda, Akio
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References Canadian Office Action (2 pages) mailed Nov. 2, 2009, in corresponding application No. 2,521,492.
(WO 95/34540) 19951200
European Office Action (5 pages) mailed Feb. 23, 2010, in corresponding application No. 04 729 502.7.
(WO-95/06035) 19950300
Matsuhisa et al. (6340678) 20020100
(1445253) 20040800
Ogawa et al. (6335327) 20020100
Office Action received Aug. 31, 2007, in related application 2005136863.
Koshio et al. (7183271) 20070200
(WO 03/042181) 20030500
(9-221475) 19970800
(2 137 760) 19990900
Ogawa et al. (6642223) 20031100
(WO-97/22591) 19970600
Neal et al. (6547395) 20030400
(WO-99/06409) 19990200
Del Tredici et al., Identification of Novel Selective V.sub.2 Receptor Non-Peptide Agonists, Biochemical Pharmacology, vol. 76, pp. 1134-1141, 2008.
Ogawa et al. (6096735) 20000800
(WO-00/46224) 20000800
Israeli Office Action (1 page) mailed Aug. 17, 2009, in corresponding application No. 171332.
Taniguchi et al. (5710150) 19980100
(3215910) 20010800
Kondo et al., "Novel Design of Nonpeptide AVP V2 Receptor Agonists: Structural Requirements for and Agonist Having 1-(4-AminobenzoyI)-2,3,4,5-tetrahydro-1H-1-benzazepine as a Template," J. med. Chem. (Nov. 2000) vol. 43, No. 23, pp. 4388-4397.
(2000-351768) 20001200
European Search Report received Jun. 25, 2008, in corresponding application EP 04 72 9502.
(8-301848) 19961100
(11-349570) 19991200
Ogawa et al. (6096736) 20000800
(9-221476) 19970800
Ogawa et al.; "Pharmaceutical Composition"; Patent Abstracts of Japan of JP 11-060488, Mar. 2, 1999.
Ogawa et al. (2002/0049194) 20020400
(WO-01/49682) 20010700
(WO-98/39325) 19980900
Ashworth et al. (2003/0087892) 20030500
(0716083) 19960600
(0987264) 20000300
(WO-99/06403) 19990200
(2926335) 19990500
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Snippet A novel 4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine derivative or a pharmaceutically acceptable salt thereof, which is useful as an agent for treating or...
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Title 4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine derivative or salt thereof
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