Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives

• Main Authors: Davis, S. Christopher, Grate, John H, Gray, David R, Gruber, John M, Huisman, Gjalt W, Ma, Steven K, Newman, Lisa M, Sheldon, Roger, Wang, Li A
• Format: Patent
• Language: English
• Published: 05.10.2010

The present invention provides methods and compositions for preparing 4-substituted 3-hydroxybutyric acid derivatives by halohydrin dehalogenase-catalyzed conversion of 4-halo-3-hydroxybutyric acid derivatives. The present invention further provides methods and compositions for preparing 4-halo-3-hy...