Substituted 7,8-dihydro-1H-pyrimido[4,5-B][1,4]diazepin-4-amines are novel kinase inhibitors

Compounds having the Formula (I) are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.

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Bibliographic Details
Main Authors Gracias, Vijaya J, Abad-Zapatero, Celerino, Djuric, Stevan W, Ji, Zhiqin, Michaelides, Michael R, Stewart, Kent D, Zanze, Irini
Format Patent
LanguageEnglish
Published 14.09.2010
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Summary:Compounds having the Formula (I) are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.