System, program product, and methods for attenuation correction of emission data on PET/CT and SPEC/CT

Embodiments of the present invention provide the use of average CT (ACT) to match the temporal resolution of CT and PET to enhance PET imaging and evaluated tumor quantification with HCT and ACT. For example, an embodiment of a method of enhanced PET imaging on a PET/CT scanner includes generating a...

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Main Authors Pan, Tinsu, Mawlawi, Osama, Luo, Dershan, Kohlmyer, Steven G, Hurley, Dennis P
Format Patent
LanguageEnglish
Published 31.08.2010
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Abstract Embodiments of the present invention provide the use of average CT (ACT) to match the temporal resolution of CT and PET to enhance PET imaging and evaluated tumor quantification with HCT and ACT. For example, an embodiment of a method of enhanced PET imaging on a PET/CT scanner includes generating an average CT scan responsive to 4D CT emission image data to thereby correct attenuation in PET emission image data. Another embodiment of a method of attenuation correction in a PET/CT scan includes averaging a plurality of consecutive low dose CT images of approximately one breathing cycle to thereby obtain an average CT.
AbstractList Embodiments of the present invention provide the use of average CT (ACT) to match the temporal resolution of CT and PET to enhance PET imaging and evaluated tumor quantification with HCT and ACT. For example, an embodiment of a method of enhanced PET imaging on a PET/CT scanner includes generating an average CT scan responsive to 4D CT emission image data to thereby correct attenuation in PET emission image data. Another embodiment of a method of attenuation correction in a PET/CT scan includes averaging a plurality of consecutive low dose CT images of approximately one breathing cycle to thereby obtain an average CT.
Author Hurley, Dennis P
Mawlawi, Osama
Luo, Dershan
Pan, Tinsu
Kohlmyer, Steven G
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Board Of Regents, The University of Texas System
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References Nehmeh SA, Erdi YE, Pan T, et al. Quantitation of respiratory motion during 4D-PET/CT acquisition acquisition, Med Phys. 2004; 31:1333-1338.
Pan et al. (2004/0081269) 20040400
Pan T, Lee TY, Rietz E, Chen GTY. 4D-CT imaging of a volume influenced by respiratory motion on multi-slice CT. Med Phys. 2004; 31:333-340.
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Osman MM, Cohade C, Nakamoto Y, Wahl RL. Respiratory motion artifacts on PET emission images obtained using CT attenuation correction on PET-CT. Eur J Nucl Med Mol Imaging. 2003;30:603-606.
Goerres GW, Kamel E, Heidelberg TN, Schwitter MR, Burger C, von Schulthess GK. PET-CT image co-registration in the thorax: influence of respiration. Eur J Nucl Med Mol Imaging. 2002; 29:361-360.
Burger C, Goerres GW, Schoenes S, Buck A, Lonn AHR, von Schulthess GK. PET attenuation coefficients from CT images: experimental evaluation of the transformation of CT into PET 511-keV attenuation coefficients. Eur J Nucl Med. 2002; 29:922-927.
Beyer T, Antoch G, Mueller S, et al. Acquisition protocol considerations for combined PET/CT imaging. J Nucl Med. 2004; 45 (Suppl): 25S-35S.
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