Medicinal concentrate of arbovirus specific immunoglobulins and F(ab)'2 and/or Fab fragments
The invention concerns a new medicinal product for the treatment of arboviruses, i.e.. a concentrate of immunoglobulins and F(ab)′2 and/or Fab fragments specific to said arbovirus as well as its process of preparation.
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| Main Author | |
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| Format | Patent |
| Language | English |
| Published |
10.08.2010
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| Online Access | Get full text |
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| Abstract | The invention concerns a new medicinal product for the treatment of arboviruses, i.e.. a concentrate of immunoglobulins and F(ab)′2 and/or Fab fragments specific to said arbovirus as well as its process of preparation. |
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| AbstractList | The invention concerns a new medicinal product for the treatment of arboviruses, i.e.. a concentrate of immunoglobulins and F(ab)′2 and/or Fab fragments specific to said arbovirus as well as its process of preparation. |
| Author | Schmitthaeusler, Roland |
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| References | (1385886) 20021100 Edelman R. et al., "Phase II safety and immunogenecity study of live chikungunya virus vaccine," Jun. 2000, Am. J. Trop. Med. Hyg., 62:681-5. Kreil et al. Journal of Virology 71: 2921-2927 (1997). Van Furth et al. The Journal of Infectious Diseases 149:511-517 (1984). Erlich et al. Antimicrobial Agents and Chemotherapy 31: 1006-1009 (1987). Ohara et al., "Prophylactic Efficacy of mmune erum Globulin against Hepatitis A," Jpn J. Exp. Med. 1986, 56(5):229-33. Dreffier, et al., "Immunoprophylaxie des infections respiratoires," Medicine/Sciences 2004, vol. 20, pp. 999-1003. Oncley et al., "The Separation of the Antibodies, Isoagglutinins, Prothrmbin, Plasminogen and B1-Lipoprotein into Subfractions of Human Plasma," 1949 J. Am. Chem. Soc. 71:541. Steele et al. Journal of Clinical Microbiology 27:640-643 (1989). Pialoux et al., "Chikungunya virus invection: review through an epidemic," Medecine et maladies infectieuses 36 (2006) pp. 253-263. Boere et al. Journal of Virology 54:546-551 (1985). A. Hamdan et al., "Possible benefit of Intravenous Immunoglobulin Therapy in Lung Transplant Recipient with West Nile Virus Encephalitis" Transplant Infectious Diseases, vol. 4, No. 3, Sep. 2002, pp. 160-162. Cruse et al. "Illustrated Dictionary of Immunology." CRC press, Boca Raton, FL, 1995, p. 107. Kunishige M, et al., "Preferential gray matter involvement in dengue myelitis," Neurology, Nov. 2004, vol. 63, No. 10, pp. 1980-1981. Gaidamovitch et al. 1973 (Database EMBASE). Ben-Nathan et al. The Journal of Infectious Diseases 188:5-12 (2003). Shimoni et al. Emerging Infectious Diseases 7(4):759 (2001). Chamberlain et al. (2005/0182080) 20050800 Thullier et al (Journal of Biotechnology 69:183-190, 1999). Van de Water et al., "Rapid in vitro micro-cytotoxicity tests for the detection and quantitation of neutralizing antibodies to both viruses and toxins," Journal of Immunological methods 166(1993): 157-164. Igarashi et al. (Passive immunization of mice with rabbit antisera against Chikungunya virus and its components, Biken Journal, 1971, vol. 14, pp. 353-355. Bayry Jagadeesh et al., "Intravenous immunoglobulin for infectious diseases: tailor-made or universal?" The Journal of Infectious Diseases, Nov. 15, 2003, vol. 188, No. 10, p. 1610. Briolant et al., "In vitro inhibition of Chikungunya and Semliki Forest viruses replication by antiviral compounds: synergistic effect of enterferon-α and ribavirin combination," 2004. Giovarelli et al. "Effect of Anti-u-Chain Specific Immunosuppression on Chikungunya Virus Encephalitis of Mice," Infection and Immunity, vol. 16, No. 3, Jun. 1977, pp. 849-852. Steinbuch M., "The isolation of IgG From Mammalian Sera with the Aid of Caprylic Actid," Archiv. Biochem. Biophys., 134:279-284 (1969). (WO2004091656) 20041000 Conrad Me et al., "Prevention of Endemic Icteric Viral Hepatitis by Administration of Immune Serum Gamma Globulin," J. Infect. Dis. 1987, 156(1):56-63. Pastorino et al., "Epidemic Resurgence of Chikungunya Virus in Democratic Republic of the Congo"Journal of Medical Virology, 2004, vol. 74, pp. 277-282. Agrawal et al. The Journal of Infectious Diseases 188:1-4 (2003). |
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| Title | Medicinal concentrate of arbovirus specific immunoglobulins and F(ab)'2 and/or Fab fragments |
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