Substituted imidazoles

This invention relates to a range of alpha substituted 2-benzyl substituted imidazole compounds and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes for their synthesis and their use as parasiticides.

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Main Authors Chubb, Nathan Anthony Logan, Cox, Mark Roger, Dauvergne, Jerome Sebastien, Ewin, Richard Andrew, Lauret, Christelle
Format Patent
LanguageEnglish
Published 22.09.2009
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Abstract This invention relates to a range of alpha substituted 2-benzyl substituted imidazole compounds and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes for their synthesis and their use as parasiticides.
AbstractList This invention relates to a range of alpha substituted 2-benzyl substituted imidazole compounds and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes for their synthesis and their use as parasiticides.
Author Chubb, Nathan Anthony Logan
Lauret, Christelle
Ewin, Richard Andrew
Dauvergne, Jerome Sebastien
Cox, Mark Roger
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Nardi et al., "Research Research on durene derivatives. Note I-hypertensive activity of 2-(2,3,5,6-tetramethylbenzyl) imidazoline and related compounds", Farmaco, Ed. Sci., 34(9):789-801, 1979.
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Allegretti et al. (2007/0155717) 20070700
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Ettmayer, Peter, Medicinal Chemistry, Lessons Learned from Marketed and Investigational Prodrugs, 47(10) (2004) 2394-2404.
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