2,4,6-Triamino-1,3,5-triazine derivative

This invention relates to an anti-dementia agent which uses a BEC 1 potassium channel inhibitor as the active ingredient.It was proved that the BEC 1 potassium channel inhibitor has an action to improve learning disorder and is useful as a preventive or therapeutic agent for diseases, preferably dem...

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Main Authors Kubota, Hideki, Suzuki, Takeshi, Miura, Masanori, Nakai, Eiichi, Yahiro, Kiyoshi, Miyake, Akira, Mochizuki, Shinobu, Nakatou, Kazuhiro
Format Patent
LanguageEnglish
Published 20.05.2008
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Abstract This invention relates to an anti-dementia agent which uses a BEC 1 potassium channel inhibitor as the active ingredient.It was proved that the BEC 1 potassium channel inhibitor has an action to improve learning disorder and is useful as a preventive or therapeutic agent for diseases, preferably dementia, in which the BEC 1 potassium channel is considered to be concerned.Illustratively, it was confirmed by an in vivo test that the BEC 1 potassium channel inhibitor has an action to improve learning disorder.Also, it was found that a compound having 2,4,6-triamino-1,3,5-triazine has a BEC 1 potassium channel inhibitory action.
AbstractList This invention relates to an anti-dementia agent which uses a BEC 1 potassium channel inhibitor as the active ingredient.It was proved that the BEC 1 potassium channel inhibitor has an action to improve learning disorder and is useful as a preventive or therapeutic agent for diseases, preferably dementia, in which the BEC 1 potassium channel is considered to be concerned.Illustratively, it was confirmed by an in vivo test that the BEC 1 potassium channel inhibitor has an action to improve learning disorder.Also, it was found that a compound having 2,4,6-triamino-1,3,5-triazine has a BEC 1 potassium channel inhibitory action.
Author Kubota, Hideki
Nakatou, Kazuhiro
Suzuki, Takeshi
Yahiro, Kiyoshi
Nakai, Eiichi
Miyake, Akira
Mochizuki, Shinobu
Miura, Masanori
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  surname: Suzuki
  fullname: Suzuki, Takeshi
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  givenname: Masanori
  surname: Miura
  fullname: Miura, Masanori
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  givenname: Eiichi
  surname: Nakai
  fullname: Nakai, Eiichi
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  givenname: Kiyoshi
  surname: Yahiro
  fullname: Yahiro, Kiyoshi
– sequence: 6
  givenname: Akira
  surname: Miyake
  fullname: Miyake, Akira
– sequence: 7
  givenname: Shinobu
  surname: Mochizuki
  fullname: Mochizuki, Shinobu
– sequence: 8
  givenname: Kazuhiro
  surname: Nakatou
  fullname: Nakatou, Kazuhiro
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Snippet This invention relates to an anti-dementia agent which uses a BEC 1 potassium channel inhibitor as the active ingredient.It was proved that the BEC 1 potassium...
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