GSK3 polypeptides

The invention provides truncated GSK3 polypeptides capable of crystallization, including GSK3α and GSK3β polypeptides, and use of these polypeptides to identify and optimize GSK3 inhibitors. Also provided are GSK3 polypeptides having at least one substituted amino acid that differs from wild-type GS...

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Bibliographic Details
Main Authors Harrison, Stephen D, Hall, John A, Calderon-Cacia, Maria, Zhong, Ziyang, Fang, Eric Y, Coit, Doris G, Nguyen, Steve H, Medina-Selby, Angelica
Format Patent
LanguageEnglish
Published 22.04.2008
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