Optimized bacterial host strains of

30 40 40 Methanotrophic bacterial strains are provided that have been optimized for the production of carotenoid compounds through the down-regulation of one or more of the crtN1, ald, crtN2 and crtN3 genes of the carotenoid biosynthetic pathway. The resulting strains lack pigmented Ccarotenoid comp...

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Main Authors Sharpe, Pamela L, Cheng, Qiong, Bosak, Melissa D, Tao, Luan, Sedkova, Natalia
Format Patent
LanguageEnglish
Published 19.06.2007
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Abstract 30 40 40 Methanotrophic bacterial strains are provided that have been optimized for the production of carotenoid compounds through the down-regulation of one or more of the crtN1, ald, crtN2 and crtN3 genes of the carotenoid biosynthetic pathway. The resulting strains lack pigmented Ccarotenoid compounds, and show an increase in the production of Ccarotenoids. The use of the optimized host strains for the production of the Ccarotenoids canthaxanthin and astaxanthin is also described.
AbstractList 30 40 40 Methanotrophic bacterial strains are provided that have been optimized for the production of carotenoid compounds through the down-regulation of one or more of the crtN1, ald, crtN2 and crtN3 genes of the carotenoid biosynthetic pathway. The resulting strains lack pigmented Ccarotenoid compounds, and show an increase in the production of Ccarotenoids. The use of the optimized host strains for the production of the Ccarotenoids canthaxanthin and astaxanthin is also described.
Author Sedkova, Natalia
Sharpe, Pamela L
Cheng, Qiong
Bosak, Melissa D
Tao, Luan
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