1-(amino)indanes and (1,2-dihydro-3-amino)-benzofurans, benzothiophenes and indoles as Edg receptor agonists

The present invention encompasses compounds of Formula (I): as well as the pharmaceutically acceptable salts and hydrates thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions an...

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Main Authors Doherty, George A, Hale, Jeffrey J, Mills, Sander G
Format Patent
LanguageEnglish
Published 22.05.2007
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Abstract The present invention encompasses compounds of Formula (I): as well as the pharmaceutically acceptable salts and hydrates thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.
AbstractList The present invention encompasses compounds of Formula (I): as well as the pharmaceutically acceptable salts and hydrates thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.
Author Hale, Jeffrey J
Doherty, George A
Mills, Sander G
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  givenname: Sander G
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References Watanabe et al. (6495578) 20021200
(WO 03/074008) 20030900
(WO 03/073986) 20030900
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Hortobagyi, G., Oct. 1, 1998, N Engl J Med, 339, 974-984.
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(WO 03/061567) 20030700
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Snippet The present invention encompasses compounds of Formula (I): as well as the pharmaceutically acceptable salts and hydrates thereof. The compounds are useful for...
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Title 1-(amino)indanes and (1,2-dihydro-3-amino)-benzofurans, benzothiophenes and indoles as Edg receptor agonists
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