FXR NR1H4 nuclear receptor binding compounds

The invention provides compounds according to the general formula which bind to the NRH receptor and act as agonists, antagonists or mixed agonists/antagonists of the NRH receptor. The invention further provides methods of treating diseases and/or conditions through binding of the nuclear receptor b...

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Main Authors Bauer, Ulrike, Cheruvallath, Zach, Deuschle, Ulrich, Dneprovskaia, Elena, Gahman, Tim, Giegrich, Kristina, Hanecak, Ronnie, Hébert, Normand, Kiely, John, Kober, Ingo, Kögl, Manfred, Kranz, Harald, Kremoser, Claus, Lee, Matthew, Otte, Kerstin, Sage, Carlton, Sud, Manish
Format Patent
LanguageEnglish
Published 29.08.2006
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Summary:The invention provides compounds according to the general formula which bind to the NRH receptor and act as agonists, antagonists or mixed agonists/antagonists of the NRH receptor. The invention further provides methods of treating diseases and/or conditions through binding of the nuclear receptor by the compounds and the production of medicaments using the compounds.