Methanotrophic carbon metabolism pathway genes and enzymes

The invention relates to the field of molecular biology and microbiology. More specifically, the invention relates to genes involved in the conversion of hexose sugars into 3-carbon metabolites in methanotrophic bacteria. Genes have been isolated from a Methylomonas sp encoding enzymes in the carbon...

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Bibliographic Details
Main Authors Koffas, Mattheos, Norton, Kelley C, Odom, James M, Ye, Rick W
Format Patent
LanguageEnglish
Published 29.04.2003
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Summary:The invention relates to the field of molecular biology and microbiology. More specifically, the invention relates to genes involved in the conversion of hexose sugars into 3-carbon metabolites in methanotrophic bacteria. Genes have been isolated from a Methylomonas sp encoding enzymes in the carbon flux pathway. The genes encode a 2-keto-3-deoxy-6-phosphogluconate (KDPGA) and a fructose bisphosphate aldolase (FFBPA), as well as numerous other genes. The genes will be useful in C1 metabolizing microorganisms for the manipulation of the carbon flux pathway.