Methods for the treatment of itching comprising administering PGD2 receptor antagonist

The present invention relates to a pharmaceutical composition for the prevention or treatment of itching comprising a prostaglandin D (PGD ) receptor antagonist. A PGDreceptor antagonist such as a compound of the formula (IA-a-5): a pharmaceutical acceptable salt thereof or a hydrate thereof, has an...

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Main Author Arimura, Akinori
Format Patent
LanguageEnglish
Published 14.01.2003
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Abstract The present invention relates to a pharmaceutical composition for the prevention or treatment of itching comprising a prostaglandin D (PGD ) receptor antagonist. A PGDreceptor antagonist such as a compound of the formula (IA-a-5): a pharmaceutical acceptable salt thereof or a hydrate thereof, has an efficacious activity for the prevention or treatment of itching and is useful as a medicament.
AbstractList The present invention relates to a pharmaceutical composition for the prevention or treatment of itching comprising a prostaglandin D (PGD ) receptor antagonist. A PGDreceptor antagonist such as a compound of the formula (IA-a-5): a pharmaceutical acceptable salt thereof or a hydrate thereof, has an efficacious activity for the prevention or treatment of itching and is useful as a medicament.
Author Arimura, Akinori
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References Nippon Kagaku Zasshi, 88(7):758-763 (1967), Chemical Society of Japan.
Cross et al., "Selective Thromboxane Synthetase Inhibitors. 3. 1H-Imidazol-1-yl-Substituted Benzo[ ]furan-, Benzo[ ] thiophene-, and Indole-2- and -3 carboxylic Acids," J. Med. Chem., 29:1637-1643 (1986) The American Chemical Society.
D.F. Woodward, et al., "Characterization of Receptor Subtypes Involved in Prostanoid-Induced Conjunctival", The Journal of Pharmacology and Experimental Therapeutics, vol. 279, No. 1, , pp. 137-142 (1996).
Nippon Kagaju Zasshi, 86(10):1067-1072 (1965), Chemical Society of Japan.
Shin-Jikken-Kagaku-Koza, vol. 14, 1787 (1978), Chemical Society of Japan.
(97/44031) 19971100
Titus and Titus, "2-Amino-3-(6-methoxybenzo[ ] thien-3-yl)propanoic Acid (1),".
Hagishita et al. (4904819) 19900200
Hannoun et al., "alpha-Phenypropionic Acid Derivatives Synthesis and Dethiation of 5-Benzoylbenzo[ ] thiophene-3-carboxylic Acid," J. Heterocyclic. Chem., 19:1131-1136 (1982), Hetero Corporation.
(3 204815) 19910600
J. Heterocycle, Chem., 10:679-681 (1973), Hetero Corporation.
Seno and Hagishita, "Thromboxane A2Receptor Antagonists. III. Synthesis and Pharmacological Activity of 6,6-Dimethylbicyclo[3. 1. 1]heptane Derivatives with a Substituted Sulfonylamino Group at C-2," Chem. Pharm. Bull., 37(6):1524-1533 (1989), Pharmaceutical Society of Japan.
Musoh et al., "Scratching behavior in mice associated with IgE-mediated allergic cutaneous reaction and its pharmacological characterization," Allergology Int., 46:117-124 (1997), Japanese Society of Allergology.
Martin-Smith and Sneader, "Beno[ ]thiophen Derivatives. Part VI. The Synthesis of 3-(2-Amino-ethyl)-5-hydroxybenzo[ ]thiophen and Related Compounds," J. Chem. Soc., (C) pp. 1899-1905 (1967), Royal Society of Chemistry.
Miyake et al. (4792550) 19881200
Ohtani et al. (6172113) 20010100
Arai et al. (5168101) 19921200
(97/00853) 19970900
Shin-Jikken-Kagaku-Koza, vol. 22, 115 (1992), Chemical Society of Japan.
(0 837 052) 19980400
Hamada and Yonemitsu, "An Improved Synthesis of Arylsulfonyl Chlorides from Aryl Halides," Synthesispp. 852-854 (1986), Georg Thieme Verlag.
Frost (4923875) 19900500
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