Methods for the treatment of itching comprising administering PGD2 receptor antagonist
The present invention relates to a pharmaceutical composition for the prevention or treatment of itching comprising a prostaglandin D (PGD ) receptor antagonist. A PGDreceptor antagonist such as a compound of the formula (IA-a-5): a pharmaceutical acceptable salt thereof or a hydrate thereof, has an...
Saved in:
Main Author | |
---|---|
Format | Patent |
Language | English |
Published |
14.01.2003
|
Online Access | Get full text |
Cover
Loading…
Abstract | The present invention relates to a pharmaceutical composition for the prevention or treatment of itching comprising a prostaglandin D
(PGD
) receptor antagonist.
A PGDreceptor antagonist such as a compound of the formula (IA-a-5): a pharmaceutical acceptable salt thereof or a hydrate thereof, has an efficacious activity for the prevention or treatment of itching and is useful as a medicament. |
---|---|
AbstractList | The present invention relates to a pharmaceutical composition for the prevention or treatment of itching comprising a prostaglandin D
(PGD
) receptor antagonist.
A PGDreceptor antagonist such as a compound of the formula (IA-a-5): a pharmaceutical acceptable salt thereof or a hydrate thereof, has an efficacious activity for the prevention or treatment of itching and is useful as a medicament. |
Author | Arimura, Akinori |
Author_xml | – sequence: 1 fullname: Arimura, Akinori |
BookMark | eNqNjEkKAjEQRbPQhdMd6gJCo9jq2nEjuBC3UqSrk4BJhUp5fzvgAVy9__nD1IwSJ5qY543Uc1egZwH1BCqEGikpcA9BrQ_JgeWYJZQqsYshhaIk1d0vxxUIWco67DEpOq7p3Ix7fBda_DgzcD49Dtflp2TU4b28nGBF026adrvbr_-ofAEfQDx4 |
ContentType | Patent |
CorporateAuthor | Shionogi & Co., Ltd |
CorporateAuthor_xml | – name: Shionogi & Co., Ltd |
DBID | EFH |
DatabaseName | USPTO Issued Patents |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EFH name: USPTO Issued Patents url: http://www.uspto.gov/patft/index.html sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
ExternalDocumentID | 06506789 |
GroupedDBID | EFH |
ID | FETCH-uspatents_grants_065067893 |
IEDL.DBID | EFH |
IngestDate | Sun Mar 05 22:31:52 EST 2023 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | English |
LinkModel | DirectLink |
MergedId | FETCHMERGED-uspatents_grants_065067893 |
OpenAccessLink | https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6506789 |
ParticipantIDs | uspatents_grants_06506789 |
PatentNumber | 6506789 |
PublicationCentury | 2000 |
PublicationDate | 20030114 |
PublicationDateYYYYMMDD | 2003-01-14 |
PublicationDate_xml | – month: 01 year: 2003 text: 20030114 day: 14 |
PublicationDecade | 2000 |
PublicationYear | 2003 |
References | Nippon Kagaku Zasshi, 88(7):758-763 (1967), Chemical Society of Japan. Cross et al., "Selective Thromboxane Synthetase Inhibitors. 3. 1H-Imidazol-1-yl-Substituted Benzo[ ]furan-, Benzo[ ] thiophene-, and Indole-2- and -3 carboxylic Acids," J. Med. Chem., 29:1637-1643 (1986) The American Chemical Society. D.F. Woodward, et al., "Characterization of Receptor Subtypes Involved in Prostanoid-Induced Conjunctival", The Journal of Pharmacology and Experimental Therapeutics, vol. 279, No. 1, , pp. 137-142 (1996). Nippon Kagaju Zasshi, 86(10):1067-1072 (1965), Chemical Society of Japan. Shin-Jikken-Kagaku-Koza, vol. 14, 1787 (1978), Chemical Society of Japan. (97/44031) 19971100 Titus and Titus, "2-Amino-3-(6-methoxybenzo[ ] thien-3-yl)propanoic Acid (1),". Hagishita et al. (4904819) 19900200 Hannoun et al., "alpha-Phenypropionic Acid Derivatives Synthesis and Dethiation of 5-Benzoylbenzo[ ] thiophene-3-carboxylic Acid," J. Heterocyclic. Chem., 19:1131-1136 (1982), Hetero Corporation. (3 204815) 19910600 J. Heterocycle, Chem., 10:679-681 (1973), Hetero Corporation. Seno and Hagishita, "Thromboxane A2Receptor Antagonists. III. Synthesis and Pharmacological Activity of 6,6-Dimethylbicyclo[3. 1. 1]heptane Derivatives with a Substituted Sulfonylamino Group at C-2," Chem. Pharm. Bull., 37(6):1524-1533 (1989), Pharmaceutical Society of Japan. Musoh et al., "Scratching behavior in mice associated with IgE-mediated allergic cutaneous reaction and its pharmacological characterization," Allergology Int., 46:117-124 (1997), Japanese Society of Allergology. Martin-Smith and Sneader, "Beno[ ]thiophen Derivatives. Part VI. The Synthesis of 3-(2-Amino-ethyl)-5-hydroxybenzo[ ]thiophen and Related Compounds," J. Chem. Soc., (C) pp. 1899-1905 (1967), Royal Society of Chemistry. Miyake et al. (4792550) 19881200 Ohtani et al. (6172113) 20010100 Arai et al. (5168101) 19921200 (97/00853) 19970900 Shin-Jikken-Kagaku-Koza, vol. 22, 115 (1992), Chemical Society of Japan. (0 837 052) 19980400 Hamada and Yonemitsu, "An Improved Synthesis of Arylsulfonyl Chlorides from Aryl Halides," Synthesispp. 852-854 (1986), Georg Thieme Verlag. Frost (4923875) 19900500 |
References_xml | – year: 19900200 ident: 4904819 contributor: fullname: Hagishita et al. – year: 19971100 ident: 97/44031 – year: 19921200 ident: 5168101 contributor: fullname: Arai et al. – year: 19900500 ident: 4923875 contributor: fullname: Frost – year: 19881200 ident: 4792550 contributor: fullname: Miyake et al. – year: 19970900 ident: 97/00853 – year: 20010100 ident: 6172113 contributor: fullname: Ohtani et al. – year: 19910600 ident: 3 204815 – year: 19980400 ident: 0 837 052 |
Score | 2.565567 |
Snippet | The present invention relates to a pharmaceutical composition for the prevention or treatment of itching comprising a prostaglandin D
(PGD
) receptor... |
SourceID | uspatents |
SourceType | Open Access Repository |
Title | Methods for the treatment of itching comprising administering PGD2 receptor antagonist |
URI | https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6506789 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfZ3fS8MwEMePbQjqk6Li_MU9-BpN26Rrn7fVIih9UNnbSEwzBG1H2-G_7yUbxRd9Kwkcx5XcfQuffgNwW5JqszSHWcTfJaMRkLDERg52kNoYqUNlPW3xHOev4nEhFwPI-39hvugYsTXl0t5t2nVXe7iS2vv2xbOt-bPzCKyc-8B39VkrUxh7T0qD-m46hGHCHdo3z_JD2KcQJNmqrv01NLIj2Cv86jEMyuoE3p78Zc0tkkxEkl3YM95YW_zoPNSIDvGmc-ce1c7X1psFYvEwC5HaU0nZNkj1UKva7Z4CZvOXac76JJarxsEtS75LNjqDEX3kl-eA6SQIIhEr0mdcCCtIRoaG6ig1lybV8RjGf4a5-GfvEg48fsYDFogrGHXNprymMdrpG1-jH_VEfkU |
link.rule.ids | 230,309,783,805,888,64367 |
linkProvider | USPTO |
linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3LTsMwEFyVgnicQIAoTx-4GvKwQ3OmhPCqcgDUW5TguKoESZWk4vcZu1XEBW6WLa1Wa3lnLI3HRJcFWJsGDnPf-ZAcEDDkQ-0bsYPMlZK5l2mrthgH8Zt4nMhJj-LuLcwXjhGfI5fmatHM28qKK9HelxvPl-bPxiOwNO4D3-VnlalE6WswDfTdcI3WgbGBvZJF8Q5tIQhIW9k2v2Aj2qWNxM7uUa8o9-n9xX7X3DAQRQbixTqVN6s0m7VW1siMyBsnzwyzlbOttQtkyf3IY2hQBfKtGSqSTSuzekAsunu9jXmXRDqtjbwldVbp-ofUxzW_OCIW3riuL4IMDM0RQgsQSU-hkjJ3pArzYECDP8Mc_7N2QZvJKEqfH8ZPJ7RttWiOy11xSv22XhRnwNQ2P7fl-gFQxYFC |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=Methods+for+the+treatment+of+itching+comprising+administering+PGD2+receptor+antagonist&rft.inventor=Arimura%2C+Akinori&rft.number=6506789&rft.date=2003-01-14&rft.externalDBID=n%2Fa&rft.externalDocID=06506789 |