Appetite-stimulating agents and remedies for anorexia

• Main Authors: Owa, Takashi, Ozawa, Yoichi, Hida, Takayuki, Miyamoto, Norimasa, Nagasu, Takeshi, Okauchi, Tatsuo, Yoshino, Hiroshi, Hata, Naoko, Yoshimatsu, Kentaro, Koyanagi, Nozomu, Kito, Kyosuke
• Format: Patent
• Language: English
• Published: 02.12.2004

An appetite-stimulating agent and a therapeutic agent for anorexia, each comprising, as an active ingredient, a sulfonamide derivative or sulfonic acid ester derivative represented by the following general formula (I): 1 wherein the ring A represents a monocyclic or bicyclic aromatic ring which may be substituted, the ring B represents a 6-membered unsaturated hydrocarbon ring or a 6-membered unsaturated heterocyclic ring containing one nitrogen atom as a heteroatom, each of which may be substituted, the ring C represents a 5-membered heterocyclic ring containing one or two nitrogen atoms, which may be substituted, W represents a single bond or -CH CH-, X represents -N(R′)- or an oxygen atom, Y represents a carbon atom or a nitrogen atom, Z represents -N(R 2 )- or a nitrogen atom, and R 1 and R 2 may be identical or different and each represents a hydrogen atom or a lower alkyl group, or a pharmacologically acceptable salt thereof, or a hydrate thereof.