Replication-defective recombinant AAV virions

The invention provides a method for producing purified replication-defective recombinant AAV virions. The method comprises introducing into a suitable host cell an AAV vector, an AAV helper construct and an adenoplasmid accessory construct into the host cell. The adenoplasmid accessory plasmid is co...

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Bibliographic Details
Main Authors Ladner, Martha Baillie, Dwarki, Varavani, Escobedo, Jaime, Zhou, Shang-Zhen
Format Patent
LanguageEnglish
Published 19.09.2002
Online AccessGet full text

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