Assay method

An assay method for determining whether an agent is capable of modulating the interaction of CCR5 and gp120 is disclosed. The method comprises incubating the agent with CCR5 and gp120 to form a first reaction mixture, and determining whether said agent modulates the interaction of CCR5 with gp120, w...

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Main Authors Dobbs, Susan, Perros, Manoussos, Rickett, Graham
Format Patent
LanguageEnglish
Published 08.11.2001
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Abstract An assay method for determining whether an agent is capable of modulating the interaction of CCR5 and gp120 is disclosed. The method comprises incubating the agent with CCR5 and gp120 to form a first reaction mixture, and determining whether said agent modulates the interaction of CCR5 with gp120, wherein said gp120 is associated with CD4. In particular, the interaction is a low affinity binding.
AbstractList An assay method for determining whether an agent is capable of modulating the interaction of CCR5 and gp120 is disclosed. The method comprises incubating the agent with CCR5 and gp120 to form a first reaction mixture, and determining whether said agent modulates the interaction of CCR5 with gp120, wherein said gp120 is associated with CD4. In particular, the interaction is a low affinity binding.
Author Dobbs, Susan
Perros, Manoussos
Rickett, Graham
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Snippet An assay method for determining whether an agent is capable of modulating the interaction of CCR5 and gp120 is disclosed. The method comprises incubating the...
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Title Assay method
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