HIV VACCINE

A method for inducing an immune response against HIV in a subject includes preparing first and second HIV-1 protein coding sequences, introducing the first and second HIV-1 protein coding sequence into first and second expression constructs using yeast homologous recombination, transfecting a cell w...

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Format Patent
LanguageEnglish
Published 02.07.2014
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Summary:A method for inducing an immune response against HIV in a subject includes preparing first and second HIV-1 protein coding sequences, introducing the first and second HIV-1 protein coding sequence into first and second expression constructs using yeast homologous recombination, transfecting a cell with the first and second, wherein the HIV-1 particle is secreted by the cell, and administering the secreted HIV-1 particle and a pharmaceutically acceptable carrier to the subject, wherein the secreted HIV-1 particle stimulates an immune response.