PROCESS FOR PREPARATION OF PURE POLYMORPHIC FORM 1 OF CLOPIDOGREL HYDROGENSULFATE

13 1414Process for the preparation of substantially pure polymorphic Form 1 of clopidogrel hydrogensulfate, wherein the reaction of optically active clopidogrel base with sulfuric acid is carried out in the mixture of at least two solvents, chosen from group I, comprising aliphatic ethers, and from...