Variants in complement regulatory genes predict age-related macular degeneration

Methods for identifying a subject at risk for developing AMD are disclosed, as are kits which can be used to practice the methods. The methods include identifying specific protective or risk polymorphisms or genotypes from the subject's genetic material, including polymorphisms in the BF, C2 an...

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LanguageEnglish
Published 13.02.2007
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Abstract Methods for identifying a subject at risk for developing AMD are disclosed, as are kits which can be used to practice the methods. The methods include identifying specific protective or risk polymorphisms or genotypes from the subject's genetic material, including polymorphisms in the BF, C2 and/or CFH genes. Microarrays and kits for use in these methods are also provided.
AbstractList Methods for identifying a subject at risk for developing AMD are disclosed, as are kits which can be used to practice the methods. The methods include identifying specific protective or risk polymorphisms or genotypes from the subject's genetic material, including polymorphisms in the BF, C2 and/or CFH genes. Microarrays and kits for use in these methods are also provided.
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CorporateAuthor The Trustees of Columbia University in The City of New York
Universtity of Iowa Research Foundation
National Institutes of Health Office of Technology Transfer
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Snippet Methods for identifying a subject at risk for developing AMD are disclosed, as are kits which can be used to practice the methods. The methods include...
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Title Variants in complement regulatory genes predict age-related macular degeneration
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