Clinical, laboratory, and molecular characteristics of a cohort of children with hemoglobinopathy S/betathalassemia

• Published in: Hematology, transfusion and cell therapy Vol. 46; no. 2; pp. 167 - 175
• Main Authors: Oliveira, Érica Louback, Belisário, André Rolim, Silva, Natiely Pereira, Rezende, Paulo Val, Muniz, Maristela Braga, Oliveira, Larissa Maira Moura, Velloso-Rodrigues, Cibele, Viana, Marcos Borato
• Format: Journal Article
• Language: Portuguese
• Published: Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular (ABHH) 2024
• Subjects: MEDICINE, GENERAL & INTERNAL; Hemoglobin Sβ0-thalassemia; Alpha-thalassemia; Hemoglobin Sβ-thalassemia; Hemoglobin Sβ+-thalassemia; Sickle cell disease

ABSTRACT Introduction: Hemoglobinopathy Sβ-thalassemia (HbSβ-thal) has a wide range of clinical and laboratory severity. There is limited information on the natural history of HbSβ-thal and its modulating factors. We described the molecular, hematological, and clinical characteristics of a cohort of...