Report of a case of probable overlap between systemic erythematous lupus and polyarteritis nodosa

ABSTRACT Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease with a wide range of clinical manifestations that may affect any organ. Polyarteritis nodosa (PAN) is defined as necrotizing inflammatory changes in the medium and small vessels, a rare form of systemic necrotizing vas...

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Published inRevista Colombiana de Reumatología Vol. 27; no. 1; pp. 61 - 64
Main Authors Schult, Sandra, Genaro, Susan, Cajas, Mirella, Ponce, Patricia
Format Journal Article
LanguagePortuguese
Published Asociación Colombiana de Reumatología 01.06.2020
Subjects
RHEUMATOLOGY
Systemic lupus erythematous
Polyarteritis nodosa
Panarteritis nudosa
Lupus eritematoso sistémico
Vasculitis de vasos medianos
Medium vessel vasculitis
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Summary:ABSTRACT Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease with a wide range of clinical manifestations that may affect any organ. Polyarteritis nodosa (PAN) is defined as necrotizing inflammatory changes in the medium and small vessels, a rare form of systemic necrotizing vasculitis in childhood. This article discusses the case of a patient with a history of deep venous thrombosis of the left leg, who presented with erythematosus purple lesions in her right hand, associated with pain, intermittent claudication, progressive limping and generalized edema. While in hospital, she was diagnosed with SLE with renal involvement and medium vessel vasculitis mainly of the upper limbs. She also met the criteria for PAN, a rare association that is seldom described in the medical literature.
ISSN:0121-8123