The probiotic Zhang-mediated correction of gut dysbiosis ameliorates peritoneal fibrosis by suppressing macrophage-related inflammation the butyrate/PPAR-γ/NF-κB pathway

• Published in: Food & function Vol. 14; no. 15; pp. 684 - 6852
• Main Authors: Wu, Zhongcai, Zuo, Xuezhi, Wang, Xiuru, Shi, Mengxia, Zhu, Han, Cao, Chujin, Liu, Xiaoqin, Liang, Wangqun, Yao, Ying, Wang, Le
• Format: Journal Article
• Published: 31.07.2023

Peritoneal fibrosis is a complication of long-term peritoneal dialysis (PD) that restricts its clinical application for the treatment of end-stage renal disease. Lactobacillus casei Zhang (LCZ), a probiotic strain isolated from traditional fermented koumiss, exhibits health benefits such as anti-inf...