Organocatalytic (3+3)-cycloaddition of -substituted phenyl nitrones with aryl cyclopropane carbaldehydes: a facile access to enantioenriched 1,2-oxazinanes

• Published in: Chemical communications (Cambridge, England) Vol. 59; no. 74; pp. 11133 - 11136
• Main Authors: Hazra, Arijit, Ghosh, Asit, Yadav, Neeraj, Banerjee, Prabal
• Format: Journal Article
• Published: 14.09.2023

The first asymmetric (3+3)-cycloaddition of ortho -substituted phenyl nitrones with aryl cyclopropane carbaldehydes has been demonstrated by secondary amine catalysts. While the other ortho -substituents gave 1,2-oxazinanes, ortho -hydroxy ones provided a novel class of tetrahydrochromeno-1,2-oxazin...