Pd-Catalysed [3 + 2]-cycloaddition towards the generation of bioactive bis-heterocycles/identification of COX-2 inhibitors analysis
In the current research, we envisaged the synthesis of bis-heterocycles containing the dihydroisoxazole ring by [3 + 2] cycloaddition of VECs (vinyl ethylene carbonates) and nitrile oxides, assisted by a Pd catalyst. Herein we explored hydroximoyl chlorides as versatile precursors for the in situ ge...
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Published in | Organic & biomolecular chemistry Vol. 2; no. 23; pp. 4746 - 4752 |
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Main Authors | , , , , , , , , |
Format | Journal Article |
Published |
15.06.2022
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Online Access | Get full text |
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