OPENchip: an on-chip molecular profiling platform for gene expression analysis and oncogenic mutation detection in single circulating tumour cells

• Published in: Lab on a chip Vol. 2; no. 5; pp. 912 - 922
• Main Authors: Lee, Amos C, Svedlund, Jessica, Darai, Evangelia, Lee, Yongju, Lee, Daewon, Lee, Han-Byoel, Kim, Sung-Min, Kim, Okju, Bae, Hyung Jong, Choi, Ahyoun, Lee, Sumin, Jeong, Yunjin, Song, Seo Woo, Choi, Yeongjae, Yeom, Huiran, Lee, Caleb S, Han, Wonshik, Lee, Dong Soon, Jang, Jin-Young, Madaboosi, Narayanan, Nilsson, Mats, Kwon, Sunghoon
• Format: Journal Article
• Language: English
• Published: 03.03.2020

Liquid biopsy holds promise towards practical implementation of personalized theranostics of cancer. In particular, circulating tumour cells (CTCs) can provide clinically actionable information that can be directly linked to prognosis or therapy decisions. In this study, gene expression patterns and...