Label free localization of nanoparticles in live cancer cells using spectroscopic microscopyElectronic supplementary information (ESI) available: ESEM images of GNP cluster surrounded by salt crystals before and after electron beam bombardment, interference image at 550 nm and quantitative colormap of RMS from HeLa cells incubated with GNPs, UV-Vis absorption spectrum of stock GNP suspension used for these studies, video GNP motion within the cell through the well-defined contrast provided in th

• Main Authors: Spicer, Graham L. C, Almassalha, Luay, Martinez, Ignacio A, Ellis, Ronald, Chandler, John E, Gladstein, Scott, Zhang, Di, Nguyen, The-Quyen, Feder, Seth, Subramanian, Hariharan, de la Rica, Roberto, Thompson, Sebastian A, Backman, Vadim
• Format: Journal Article
• Published: 18.10.2018

Gold nanoparticles (GNPs) have become essential tools used in nanobiotechnology due to their tunable plasmonic properties and low toxicity in biological samples. Among the available approaches for imaging GNPs internalized by cells, hyperspectral techniques stand out due to their ability to simultan...