Synthesis and antitumoral activity of novel analogues monastrol-fatty acids against glioma cellsElectronic supplementary information (ESI) available: 1H and 13C NMR spectra of the compounds. See DOI: 10.1039/c8md00169c

• Main Authors: De Oliveira, Franciele S, De Oliveira, Patrick M, Farias, Luana M, Brinkerhoff, Rafael C, Sobrinho, Rui Carlos M. A, Treptow, Tamara M, Montes D'Oca, Caroline R, Marinho, Marcelo A. G, Hort, Mariana A, Horn, Ana P, Russowsky, Dennis, Montes D'Oca, Marcelo G
• Format: Journal Article
• Language: English
• Published: 15.08.2018

Monastrol is a small cell-permeable heterocyclic molecule that is recognized as an inhibitor of mitotic kinesin Eg5. Heterocyclic-fatty acid derivatives are a new class of compounds with a broad range of biological activities. This work describes a comparative study of the in vitro antitumoral activ...