Iron(iii) coordination properties of ladanein, a flavone lead with a broad-spectrum antiviral activityElectronic supplementary information (ESI) available: Absorption spectrophotometric titrations of the ligands and the ferric complexes; ESI-MS characterization; oxidation kinetics of the ligands monitored by absorption spectrophotometry; ICP-MS data. See DOI: 10.1039/c7nj04867j

• Main Authors: Martin-Benlloch, X, Novodomska, A, Jacquemin, D, Davioud-Charvet, E, Elhabiri, M
• Format: Journal Article
• Language: English
• Published: 14.05.2018

Ladanein, a 5,6,7-trihydroxylayted flavone was recently shown to display potent antiviral activities toward enveloped virus particles ( e.g. , hepatitis C virus, human immunodeficiency virus, vesicular stomatitis virus). Fe( iii ) coordination and pH were suggested to be critical for bioactivation s...