The role of conformational heterogeneity in regulating the apoptotic activity of BAX proteinElectronic supplementary information (ESI) available. See DOI: 10.1039/c7cp00401j

While activation of BAX is required for initiating mitochondria-mediated apoptosis, the underlying mechanisms remain unsettled. We studied conformations of BAX protein using pressure- and temperature-resolved ESR techniques and obtained the thermodynamic properties of the conformations. We show that...

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Bibliographic Details
Main Authors Kao, Te-Yu, Tsai, Chia-Jung, Lan, Yu-Jing, Chiang, Yun-Wei
Format Journal Article
LanguageEnglish
Published 05.04.2017
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