The role of conformational heterogeneity in regulating the apoptotic activity of BAX proteinElectronic supplementary information (ESI) available. See DOI: 10.1039/c7cp00401j
While activation of BAX is required for initiating mitochondria-mediated apoptosis, the underlying mechanisms remain unsettled. We studied conformations of BAX protein using pressure- and temperature-resolved ESR techniques and obtained the thermodynamic properties of the conformations. We show that...
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Main Authors | , , , |
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Format | Journal Article |
Language | English |
Published |
05.04.2017
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Online Access | Get full text |
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