Droplet generation in cross-flow for cost-effective 3D-printed "plug-and-play" microfluidic devicesElectronic supplementary information (ESI) available: S1. W/O emulsion generation. S2. O/W emulsion generation. S3. Larger emulsion generation at the tubing back. S4. Smallest emulsion generation. S5. Emulsion generation with different concentrations. S6. Emulsion droplet coalescence. S7. Design files for printing. S8. Testing the consistency of printed gap distance. See DOI: 10.1039/c6ra11724d
Droplet-based microfluidics is a rapidly growing field of research and involves various applications from chemistry to biology. Droplet generation techniques become the pre-requisite focus. Additive manufacturing (3D printing) technology has recently been exploited in microfluidics due to its simpli...
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| Format | Journal Article |
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26.08.2016
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| Abstract | Droplet-based microfluidics is a rapidly growing field of research and involves various applications from chemistry to biology. Droplet generation techniques become the pre-requisite focus. Additive manufacturing (3D printing) technology has recently been exploited in microfluidics due to its simplicity and low cost. However, only relatively large droplets can be produced in current 3D-printed droplet generators, due to the channel dimension limitations on how fine a channel can be 3D-printed. Here we report a novel design of a 3D-printed "plug-and-play" device for the generation of monodisperse microdroplets with sizes down to ∼50 μm. This device combines a 3D-printed generator, a commercial tubing and a fingertight fitting, which can be easily assembled and disassembled. Different emulsions, water-in-oil and oil-in-water, can be generated in the same device. Scaling laws for droplet sizes generated in our device have been successfully proposed and verified. Furthermore, the feasibility of 3D printing technology used in droplet-based engineering applications has been demonstrated by two novel 3D-printed devices, as well as by using the device for producing magnetically responsive microparticles.
Novel low-cost 3D-printed plug-and-play microfluidic devices have been developed for droplet generation and applications. By combining a commercial tubing with the printed channel design we can generate well-controlled droplets down to 50 μm. |
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| AbstractList | Droplet-based microfluidics is a rapidly growing field of research and involves various applications from chemistry to biology. Droplet generation techniques become the pre-requisite focus. Additive manufacturing (3D printing) technology has recently been exploited in microfluidics due to its simplicity and low cost. However, only relatively large droplets can be produced in current 3D-printed droplet generators, due to the channel dimension limitations on how fine a channel can be 3D-printed. Here we report a novel design of a 3D-printed "plug-and-play" device for the generation of monodisperse microdroplets with sizes down to ∼50 μm. This device combines a 3D-printed generator, a commercial tubing and a fingertight fitting, which can be easily assembled and disassembled. Different emulsions, water-in-oil and oil-in-water, can be generated in the same device. Scaling laws for droplet sizes generated in our device have been successfully proposed and verified. Furthermore, the feasibility of 3D printing technology used in droplet-based engineering applications has been demonstrated by two novel 3D-printed devices, as well as by using the device for producing magnetically responsive microparticles.
Novel low-cost 3D-printed plug-and-play microfluidic devices have been developed for droplet generation and applications. By combining a commercial tubing with the printed channel design we can generate well-controlled droplets down to 50 μm. |
| Author | Li, Er Qiang Zhang, Jia Ming Thoroddsen, Sigurdur T Buttner, Ulrich Aguirre-Pablo, Andres A |
| AuthorAffiliation | King Abdullah University of Science and Technology (KAUST) Division of Physical Sciences and Engineering Clean Combustion Research Center Division of Computer Electrical and Mathematical Sciences and Engineering |
| AuthorAffiliation_xml | – name: Division of Physical Sciences and Engineering – name: Division of Computer – name: Clean Combustion Research Center – name: Electrical and Mathematical Sciences and Engineering – name: King Abdullah University of Science and Technology (KAUST) |
| Author_xml | – sequence: 1 givenname: Jia Ming surname: Zhang fullname: Zhang, Jia Ming – sequence: 2 givenname: Andres A surname: Aguirre-Pablo fullname: Aguirre-Pablo, Andres A – sequence: 3 givenname: Er Qiang surname: Li fullname: Li, Er Qiang – sequence: 4 givenname: Ulrich surname: Buttner fullname: Buttner, Ulrich – sequence: 5 givenname: Sigurdur T surname: Thoroddsen fullname: Thoroddsen, Sigurdur T |
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| Notes | 10.1039/c6ra11724d Electronic supplementary information (ESI) available: S1. W/O emulsion generation. S2. O/W emulsion generation. S3. Larger emulsion generation at the tubing back. S4. Smallest emulsion generation. S5. Emulsion generation with different concentrations. S6. Emulsion droplet coalescence. S7. Design files for printing. S8. Testing the consistency of printed gap distance. See DOI |
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| Title | Droplet generation in cross-flow for cost-effective 3D-printed "plug-and-play" microfluidic devicesElectronic supplementary information (ESI) available: S1. W/O emulsion generation. S2. O/W emulsion generation. S3. Larger emulsion generation at the tubing back. S4. Smallest emulsion generation. S5. Emulsion generation with different concentrations. S6. Emulsion droplet coalescence. S7. Design files for printing. S8. Testing the consistency of printed gap distance. See DOI: 10.1039/c6ra11724d |
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