Red-emitting, EtTP-5-based organic nanoprobes for two-photon imaging in 3D multicellular biological modelsElectronic supplementary information (ESI) available. See DOI: 10.1039/c6ra09954h

Biocompatible and biostable EtTP-5-loaded organic core-shell nanoparticles have been successfully evaluated for their potential as red-emitting fluorescent nanoprobes for two-photon imaging. Readily formed by Flash NanoPrecipitation, EtTP-5-based nanoprobes proved to penetrate well into multicellula...

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Main Authors Pinkerton, Nathalie M, Frongia, Céline, Lobjois, Valérie, Wilson, Brian K, Bruzek, Matthew J, Prud'homme, Robert K, Anthony, John, Bolze, Frédéric, Chassaing, Stefan
Format Journal Article
Published 12.07.2016
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Summary:Biocompatible and biostable EtTP-5-loaded organic core-shell nanoparticles have been successfully evaluated for their potential as red-emitting fluorescent nanoprobes for two-photon imaging. Readily formed by Flash NanoPrecipitation, EtTP-5-based nanoprobes proved to penetrate well into multicellular spheroids and were easily imaged through several cell layers within these complex, 3D tissue models. Biocompatible and biostable EtTP-5-loaded organic core-shell nanoparticles have been successfully evaluated for their potential as red-emitting fluorescent nanoprobes for two-photon imaging.
Bibliography:10.1039/c6ra09954h
Electronic supplementary information (ESI) available. See DOI
ISSN:2046-2069
DOI:10.1039/c6ra09954h