Intracellular water - an overlooked drug target? Cisplatin impact in cancer cells probed by neutronsElectronic supplementary information (ESI) available: Experimental procedures comprising: chemicals, cell culture and details on the optical vibrational spectroscopy spectrometers/data acquisition. See DOI: 10.1039/c6cp05198g

The first neutron scattering study on human nucleated cells is reported, addressing the subject of solvent-slaving to a drug by probing intracellular water upon drug exposure. Inelastic and quasi-elastic neutron scattering spectroscopy with isotope labelling was applied for monitoring interfacial wa...

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Bibliographic Details
Main Authors Marques, M. P. M, Batista de Carvalho, A. L. M, Sakai, V. Garcia, Hatter, L, Batista de Carvalho, L. A. E
Format Journal Article
LanguageEnglish
Published 25.01.2017
Online AccessGet full text

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