Solvent penetration mediated phase transformation for the preparation of aggregated particles with well-defined shape Electronic supplementary information (ESI) available: Experimental details and XRD patterns and SEM of sulfadiazine, NMP solvate and aggregates. See DOI: 10.1039/c6ce01808d

We report here a unique method for the preparation of aggregated crystals with well-defined shape and size using a solvent penetration-mediated phase transformation. An unusually fast phase transformation of sulfadiazine was observed. The aggregated sulfadiazine crystals are obtained through a water...

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Main Authors Wu, Songgu, Chen, Mingyang, Li, Kangli, Xu, Shijie, Yu, Bo, Liu, Shiyuan, Hou, Baohong, Gong, Junbo
Format Journal Article
LanguageEnglish
Published 05.12.2016
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Abstract We report here a unique method for the preparation of aggregated crystals with well-defined shape and size using a solvent penetration-mediated phase transformation. An unusually fast phase transformation of sulfadiazine was observed. The aggregated sulfadiazine crystals are obtained through a water penetration mediated transformation of sulfadiazine N -methyl pyrrolidone solvate. The aggregated particles keep the same shape and size of the parent crystals. We report here a unique method for the preparation of aggregated crystals with well-defined shape and size using a solvent penetration mediated phase transformation.
AbstractList We report here a unique method for the preparation of aggregated crystals with well-defined shape and size using a solvent penetration-mediated phase transformation. An unusually fast phase transformation of sulfadiazine was observed. The aggregated sulfadiazine crystals are obtained through a water penetration mediated transformation of sulfadiazine N -methyl pyrrolidone solvate. The aggregated particles keep the same shape and size of the parent crystals. We report here a unique method for the preparation of aggregated crystals with well-defined shape and size using a solvent penetration mediated phase transformation.
Author Liu, Shiyuan
Gong, Junbo
Chen, Mingyang
Yu, Bo
Hou, Baohong
Wu, Songgu
Li, Kangli
Xu, Shijie
AuthorAffiliation Tianjin University
Collaborative Innovation Center of Chemistry Science and Engineering
Key Laboratory Modern Drug Delivery and High Efficiency in Tianjin
State Key Laboratory of Chemical Engineering
School of Chemical Engineering and Technology
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  givenname: Songgu
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  givenname: Junbo
  surname: Gong
  fullname: Gong, Junbo
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Title Solvent penetration mediated phase transformation for the preparation of aggregated particles with well-defined shape Electronic supplementary information (ESI) available: Experimental details and XRD patterns and SEM of sulfadiazine, NMP solvate and aggregates. See DOI: 10.1039/c6ce01808d
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