Alternative synthesis of the anti-baldness compound RU58841Electronic supplementary information (ESI) available. CCDC 892388, 893326, 894556 and 904089. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4ra00332b

• Main Authors: Leonard, Matthew J, Lingham, Anthony R, Niere, Julie O, Jackson, Neale R. C, McKay, Peter G, Hügel, Helmut M
• Format: Journal Article
• Language: English
• Published: 17.03.2014

RU58841 is active against baldness and is commercially available. The previously reported synthesis uses phosgene, three discrete inert atmosphere steps and three steps that require flash chromatography. Our synthesis uses no phosgene, only one inert atmosphere step and does not require flash chroma...