An integrated optofluidic device for single-cell sorting driven by mechanical propertiesElectronic supplementary information (ESI) available. See DOI: 10.1039/c4lc01496k
We present a novel optofluidic device for real-time sorting on the basis of cell mechanical properties, measured by optical stretching. The whole mechanism, based on optical forces, does not hamper the viability of the tested cells, which can be used for further analysis. The device effectiveness is...
Saved in:
Main Authors | , , , , , , , , , , |
---|---|
Format | Journal Article |
Language | English |
Published |
16.02.2015
|
Online Access | Get full text |
Cover
Loading…
Abstract | We present a novel optofluidic device for real-time sorting on the basis of cell mechanical properties, measured by optical stretching. The whole mechanism, based on optical forces, does not hamper the viability of the tested cells, which can be used for further analysis. The device effectiveness is demonstrated by extracting a sample population enriched with highly metastatic cells from a heterogeneous cell mixture.
Cell sorting based on mechanical properties is demonstrated using an optofluidic chip by extracting highly metastatic cells from a heterogeneous population. |
---|---|
AbstractList | We present a novel optofluidic device for real-time sorting on the basis of cell mechanical properties, measured by optical stretching. The whole mechanism, based on optical forces, does not hamper the viability of the tested cells, which can be used for further analysis. The device effectiveness is demonstrated by extracting a sample population enriched with highly metastatic cells from a heterogeneous cell mixture.
Cell sorting based on mechanical properties is demonstrated using an optofluidic chip by extracting highly metastatic cells from a heterogeneous population. |
Author | Vazquez, R. Martinez Yang, T Bragheri, F Veglione, M Nava, G Osellame, R Minzioni, P Paiè, P Cristiani, I Mondello, C Di Tano, M |
AuthorAffiliation | Università di Pavia Dipartimento di Fisica Dipartimento di Ingegneria Industriale e dell'Informazione Istituto di Genetica Molecolare (IGM)-CNR Istituto di Fotonica e Nanotecnologie (IFN)-CNR Politecnico di Milano |
AuthorAffiliation_xml | – name: Istituto di Genetica Molecolare (IGM)-CNR – name: Dipartimento di Fisica – name: Istituto di Fotonica e Nanotecnologie (IFN)-CNR – name: Politecnico di Milano – name: Dipartimento di Ingegneria Industriale e dell'Informazione – name: Università di Pavia |
Author_xml | – sequence: 1 givenname: T surname: Yang fullname: Yang, T – sequence: 2 givenname: P surname: Paiè fullname: Paiè, P – sequence: 3 givenname: G surname: Nava fullname: Nava, G – sequence: 4 givenname: F surname: Bragheri fullname: Bragheri, F – sequence: 5 givenname: R. Martinez surname: Vazquez fullname: Vazquez, R. Martinez – sequence: 6 givenname: P surname: Minzioni fullname: Minzioni, P – sequence: 7 givenname: M surname: Veglione fullname: Veglione, M – sequence: 8 givenname: M surname: Di Tano fullname: Di Tano, M – sequence: 9 givenname: C surname: Mondello fullname: Mondello, C – sequence: 10 givenname: R surname: Osellame fullname: Osellame, R – sequence: 11 givenname: I surname: Cristiani fullname: Cristiani, I |
BookMark | eNqFjzFPwzAQhS1UJNrCwo50bDCk2EpoGzYEQXTqUPbItS_FcLEt243Un8S_xAOCAQmmu_e-03u6CRtZZ5Gxc8Fngpf1japIcVHV8_cjNhbVoiy4WNaj771enLBJjG-ci9tqvhyzj3sLxibcBZlQg_PJdbQ32ijQOBiF0LkA0dgdYaGQCKILKUvQwQxoYXuAHtWrtEZJAh-cx8wxNoQqBZdtiHvvCXu0SYZDbsuJvUzGWbhqNqtrkIM0JLeEM9ggwuN6dQe_Hzplx52kiGdfc8ounpqXh-ciRNX6YPoc3v6cl__zy79463VXfgLJG2zd |
ContentType | Journal Article |
DOI | 10.1039/c4lc01496k |
DatabaseTitleList | |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Engineering Chemistry Biology |
EISSN | 1473-0189 |
EndPage | 1266 |
ExternalDocumentID | c4lc01496k |
ID | FETCH-rsc_primary_c4lc01496k3 |
ISSN | 1473-0197 |
IngestDate | Thu May 19 04:18:28 EDT 2016 Sat Jun 01 02:26:39 EDT 2019 |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 5 |
Language | English |
LinkModel | OpenURL |
MergedId | FETCHMERGED-rsc_primary_c4lc01496k3 |
Notes | 10.1039/c4lc01496k Electronic supplementary information (ESI) available. See DOI |
PageCount | 5 |
ParticipantIDs | rsc_primary_c4lc01496k |
PublicationCentury | 2000 |
PublicationDate | 20150216 |
PublicationDateYYYYMMDD | 2015-02-16 |
PublicationDate_xml | – month: 2 year: 2015 text: 20150216 day: 16 |
PublicationDecade | 2010 |
PublicationYear | 2015 |
SSID | ssj0015468 |
Score | 4.3554616 |
Snippet | We present a novel optofluidic device for real-time sorting on the basis of cell mechanical properties, measured by optical stretching. The whole mechanism,... |
SourceID | rsc |
SourceType | Enrichment Source Publisher |
StartPage | 1262 |
Title | An integrated optofluidic device for single-cell sorting driven by mechanical propertiesElectronic supplementary information (ESI) available. See DOI: 10.1039/c4lc01496k |
Volume | 15 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Ra9swEBZZytj6MLZsZe3acQ972AjOXEe2676FLqUZWzdYBt1TsC0ZDKkT3KTQPvbf9F_uTrIthXqw7cUkEhYR38fldLrvjrF3QZxlIvXomBpzh4vIdRKE2gnFMEx54mZ-RkLhr-fB2U_--cK_6HTurKyl9SoZpLetupL_QRXHEFdSyf4Dss2iOICfEV98IsL4_CuMR4Up9yD6i-Vqkc3XuchT0kKhBVA5hBQMmEuHIvT9q0Wp0pxFSUaOXM9LSdJfhdSS4vIlFVgdm944V9T1U2eYlyQRbMSO5JqOf0woqhBfx_mcJFgDND2y_-nbRMUZlNSe6oymfJ7SGSloVEG_qih1k6H9Pc7Vlf3RhuTsHFdWgXvr5p_SUnKTklwFLA6VAFzrKSsby0NK4dJpuQNpj-luQo1h9i0C-paVPfQqCy7rr0Hrv0HrJjera5vJR2zLCyPf77Kt0Xg6-dLcRflcCyrrn10XuR1GH83b6JqUdcsY5ZpMn7Nn1ZkCRpogL1hHFj32WHcZvemxJyd1U78e27bqT75k96MCDIHAIhBoAgHCDRaBoCIQaAJBcgOGQNBGINggEFgEgvdInw9gyANIHkDyHMPDjb9iB6fj6cmZg9ufLXWFlJmZHu6wbrEo5GsGbhqGIsjcYShCnkZeEsUJF76XcE-6PHN32U77Grtsr31ithTZ3p_eesOeGvbts-6qXMsDdCBXydsK4d-CGHX9 |
link.rule.ids | 315,786,790,27955,27956 |
linkProvider | Royal Society of Chemistry |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=An+integrated+optofluidic+device+for+single-cell+sorting+driven+by+mechanical+propertiesElectronic+supplementary+information+%28ESI%29+available.+See+DOI%3A+10.1039%2Fc4lc01496k&rft.au=Yang%2C+T&rft.au=Pai%C3%A8%2C+P&rft.au=Nava%2C+G&rft.au=Bragheri%2C+F&rft.date=2015-02-16&rft.issn=1473-0197&rft.eissn=1473-0189&rft.volume=15&rft.issue=5&rft.spage=1262&rft.epage=1266&rft_id=info:doi/10.1039%2Fc4lc01496k&rft.externalDocID=c4lc01496k |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1473-0197&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1473-0197&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1473-0197&client=summon |