A novel Affibody bioconjugate for dual-modality imaging of ovarian cancerElectronic supplementary information (ESI) available: Materials, experimental details, characterization data, and biological assays. See DOI: 10.1039/c4cc03454f

An Affibody based dual imaging probe (PET and optical imaging) has been successfully developed. Dendrimer PAMAM G0 was used as a platform to assemble an NIRF dye, a metal chelator, and Affibody for dual modality imaging of ovarian cancer. Excellent tumor imaging quality was achieved in both modaliti...

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Bibliographic Details
Main Authors Wang, Yihong, Miao, Zheng, Ren, Gang, Xu, Yingding, Cheng, Zhen
Format Journal Article
LanguageEnglish
Published 30.09.2014
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Summary:An Affibody based dual imaging probe (PET and optical imaging) has been successfully developed. Dendrimer PAMAM G0 was used as a platform to assemble an NIRF dye, a metal chelator, and Affibody for dual modality imaging of ovarian cancer. Excellent tumor imaging quality was achieved in both modalities in the living tumor mice models. An Affibody based dual imaging probe (PET and optical imaging) has been successfully developed. Dendrimer PAMAM G0 was used as a platform to assemble an NIRF dye, a metal chelator, and Affibody for dual modality imaging of ovarian cancer. Excellent tumor imaging quality was achieved in both modalities in the living tumor mice models.
Bibliography:10.1039/c4cc03454f
Electronic supplementary information (ESI) available: Materials, experimental details, characterization data, and biological assays. See DOI
ISSN:1359-7345
1364-548X
DOI:10.1039/c4cc03454f