Solid phase synthesis of glycopeptides using Shoda's activation of unprotected carbohydratesElectronic supplementary information (ESI) available: Synthetic procedures and physical characterization of products. See DOI: 10.1039/c3cc43458c

• Main Authors: Novoa, Alexandre, Barluenga, Sofia, Serba, Christelle, Winssinger, Nicolas
• Format: Journal Article
• Language: English
• Published: 01.08.2013

An expedient and simple protocol to access S-linked glycopeptides by Fmoc SPPS using unprotected carbohydrates is reported. The utility of the method was demonstrated with the solid phase synthesis of a MUC1 fragment (20 mer) containing two glycosylation sites that were substituted with S-linked gly...