Enantioselective synthesis of bio-relevant 3,5-diaryl pyrazolinesElectronic supplementary information (ESI) available: copies of NMR spectra and HPLC chromatograms for all newly formed products. See DOI: 10.1039/c2ob25227a

• Main Authors: Mahé, Olivier, Dez, Isabelle, Levacher, Vincent, Brière, Jean-François
• Format: Journal Article
• Language: English
• Published: 24.04.2012

The straightforward asymmetric construction of bio-relevant Δ 2 -pyrazolines having either N -(thio)amide or N -acetyl functional groups and flanked by aryl substituents such as phenol at C3 and C5 has been achieved through an enantioselective phase transfer organocatalytic addition of N -Boc hydraz...